2024年12月25日 · GRK6 (G Protein-Coupled Receptor Kinase 6) is a Protein Coding gene. Diseases associated with GRK6 include Whim Syndrome 1 and Huntington Disease. Among …

GRK6 is widely and relatively evenly expressed throughout the body, but with particularly high expression in immune cells. [6] GRK6 exists in three splice variants that differ in the carboxyl …

In this review, we compile important findings concerning GRK6 regulation for a better pathophysiological understanding of the intracellular interaction in the context of inflammation …

GRK6 is potential marker for organ injury and survival after cardiopulmonary bypass; the crystalline GRK6 RGS homology domain forms an extensive dimer interface using conserved …

2021年2月18日 · Background: G protein-coupled receptor kinase 6 (GRK6) is part of the G protein-coupled receptor kinase family, whose members act as key regulators of seven …

2016年11月24日 · In this study, we demonstrate that GRK6 regulates of self-renewal and lymphoid differentiation of HSCs, and underscore its underlying importance in the …

2010年8月20日 · The analysis presents the structure of the G protein‐coupled receptor (GPCR) kinase 6 (GRK6) in an active conformation. A model of the GRK–GPCR complex is provided …

Human G-protein coupled receptor kinase 6 (GRK6) belongs to the GRK4 kinase subfamily of the G protein-coupled receptor kinase family which comprises of GRK1, GRK2, and GRK4. These …

2024年1月7日 · Title: Hypermethylation of the G protein-coupled receptor kinase 6 (GRK6) promoter inhibits binding of C/EBPα, and GRK6 knockdown promotes cell migration and …

GRK6 is a protein that plays a significant role in the regulation and desensitization of G protein-coupled receptors (GPCRs) in the brain, particularly in dopaminergic areas. It is primarily …