Science：我国科学家揭示细胞毒性淋巴细胞在靶细胞中引发细胞焦亡机制 …
2020年5月2日 · 颗粒酶家族在人类中包括5个成员：颗粒酶a（gzma）、颗粒酶b（gzmb）、颗粒酶h（gzmh）、颗粒酶k（gzmk）和颗粒酶m（gzmm），而在小鼠中包括11个成员 ...
GZMH Gene - GeneCards | GRAH Protein | GRAH Antibody
2024年12月25日 · GZMH (Granzyme H) is a Protein Coding gene. Diseases associated with GZMH include Trichothiodystrophy 7, Nonphotosensitive and Bartter Syndrome, Type 5, …
GZMH - Wikipedia
^ "Entrez Gene: GZMH granzyme H (cathepsin G-like 2, protein h-CCPX)". Waterhouse NJ, Trapani JA (2007). "H is for helper: granzyme H helps granzyme B kill adenovirus-infected …
Granzyme A - Wikipedia
Granzyme A (GzmA, EC 3.4.21.78, CTLA3, HuTPS, T-cell associated protease 1, cytotoxic T lymphocyte serine protease, TSP-1, T-cell derived serine proteinase) is a tryptase [5][6][7] and …
Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger ...
2020年4月16日 · GZMA from cytotoxic lymphocytes cleaves and activates GSDMB to induce target cell pyroptosis. This immune effector mechanism promotes CTL-mediated tumor …
Differential expression of the granzymes A, K and M and ... - PubMed
Flow cytometric analysis of peripheral blood lymphocytes revealed that GzmA, GzmM and perforin show a similar distribution. They are expressed in almost all CD16+CD56+ NK cells, …
什么是颗粒酶A (Granzyme A)？ - 知乎
颗粒酶A (Granzyme A)是 丝氨酸蛋白酶 中颗粒酶家族的一员，专门存在于 细胞毒性T淋巴细胞 (CTL)和自然杀伤 (NK)细胞的颗粒中。 Granzyme A是CTL和NK细胞中较为丰富的蛋白酶。 …
GZMH granzyme H [Homo sapiens (human)] - Gene - NCBI
2025年1月4日 · GzmH may play an essential role in caspase-dependent pathogen clearance in the innate immunity that may complement the proapoptotic function of GzmB in human NK …
Structural insights into the substrate specificity of human ... - PubMed
2012年1月15日 · Human granzyme H (GzmH) is constitutively expressed in human NK cells that have important roles in innate immune responses against tumors and viruses. GzmH is a …
Science｜来自毒性淋巴细胞的颗粒酶A通过切割GSDMB诱发靶细胞 …
导语： 2020年4月16日，来自北京生命科学研究所（NIBS）的Zhiwei Zhou等在Science上发表了题为“Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target …