a) 髓过氧化物酶 (mpo) 和瓜氨酸化组蛋白 h3 (h3cit)，分别是中性粒细胞和 net 的标志物，在乳腺癌和结肠癌患者的肝转移中含量丰富。 肝脏中 NETs (NET-DNA) 的 DNA 成分通过与 …

研究发现，在体外刺激和炎症条件下，所有检测到的NETotic中性粒细胞也表达citrullinated histone H3 (H3cit)。 这项研究不仅推动了对中性粒细胞功能的理解，也为炎症性疾病的临床诊断和治疗 …

2020年7月13日 · In the present study we have evaluated circulating H3cit in stable asthmatics and investigated its relationship with asthma severity, pulmonary function and selected blood …

Objectives To investigate whether the levels of citrullinated histone H3 (H3Cit), a biomarker for NET formation, cell-free DNA (cfDNA) and nucleosomes predict venous thromboembolism …

In this study, we investigated whether citrullinated histone H3 (H3Cit) could serve as a biomarker for the detection of critical liver damage in sepsis and the efficacy of phosphodiesterase-III …

目的 研究瓜氨酸组蛋白 H3 (H3Cit)（NET 形成的生物标志物）、游离 DNA (cfDNA) 和核小体的水平是否可以预测癌症患者的静脉血栓栓塞 (VTE)。 患者/方法 946 名新诊断癌症或缓解后病情 …

2018年8月23日 · In a randomized and placebo-controlled human model of endotoxemia (lipopolysaccharide injection; LPS), we now report significant LPS-induced elevations of …

Recent data propose a diagnostic and prognostic capacity for citrullinated histone H3 (H3Cit), a marker of neutrophil extracellular traps (NETs), in pathologic conditions such as cancer and …

H3Cit immunostaining is a useful tool for identifying activated neutrophils. The frequency of H3Cit+ neutrophils is not only a disease-specific marker but also a potential marker for …

Prior studies indicate that neutrophil extracellular traps (NETs) are associated with arterial thromboembolism (ATE) and mortality. We investigated the association between NET …