
Cellosaurus cell line HB1.F3 (CVCL_LJ44)
Human neural stem cells genetically modified for brain repair in neurological disorders. Stable expression of neurogenin 1 induces LGR5, a novel stem cell marker, in an immortalized …
A Potential Therapy Using Engineered Stem Cells Prevented …
2018年9月14日 · In the present study, human neural stem cells (hNSCs) with tumor-tropic behavior were used as drug delivery vehicle to selectively target melanoma. A hNSC line …
Pharmacokinetic study of neural stem cell-based cell carrier for ...
2012年5月4日 · Here, we report the characterization of an FDA approved NSC, HB1.F3-CD, as a cell carrier for CRAd-S-pk7, a glioma-tropic oncolytic adenovirus. We show that NSCs …
Cellosaurus cell line HB1.F3.CD21 (CVCL_LJ45)
Cell type: Neural stem cell; CL= CL_0000047. L-MYC expression maintains self-renewal and prolongs multipotency of primary human neural stem cells.
Genetically engineered human neural stem cells for brain repair …
2007年5月1日 · NSCs can circumvent blood–brain barrier and migrate to the specific pathologic areas of brain with trophism. We introduced HB1.F3 immortalized human NSCs intravenously …
Human neural stem cells target experimental intracranial ...
2006年9月15日 · As proof-of-concept, we used HB1.F3 cells engineered to secrete the prodrug activating enzyme cytosine deaminase. We investigated the potential of human NSCs to …
HB1.F3-CD(HB1.F3-CD) - _专利_临床_研发 - synapse.zhihuiya.com
Here, we report the characterization of an FDA approved NSC, HB1.F3-CD, as a cell carrier for CRAd-S-pk7, a glioma-tropic oncolytic adenovirus. We show that NSCs replicate and release …
Selective antitumor effect of neural stem cells expressing cytosine ...
In this study, we employed human neural stem cells (HB1.F3; hNSCs) transduced with genes expressing Escherichia coli cytosine deaminase (HB1.F3.CD) and human interferon-beta …
HB1.F3.CD neural stem cells (NSCs) transduced with
HB1.F3.CD neural stem cells (NSCs) transduced with adenoviral vectors encoding rCE or hCE1m6 produce functional enzymes, retain tumor tropism, and enhance killing of glioma …
A human neural stem cell line provides neuroprotection and …
2016年1月15日 · A human neural stem cell line, HB1.F3, demonstrated neuroprotective properties in cerebral ischemia animal models. In this study, we have investigated about the mechanisms …