
HCC827 Cell Line - an overview | ScienceDirect Topics
Chen and colleagues (T. Chen et al., 2019), for example, employed Osimertinib-resistant H1975 and HCC827 cell lines to deepen the role exerted by circular RNAs and the role they played in …
EGFR over-expression in non-small cell lung cancers harboring …
H1650, H1975, and HCC827 cells were cultured in the same media as H1299 cells. PE089 cell line was cultured in DMEM basal medium supplemented with 10% FCS plus penicillin and …
ER2, a novel human anti-EGFR monoclonal antibody
2016年5月1日 · Antitumor Effect of ER2 on H322, HCC827 and A549 xenograft models H322, HCC827 and A549 cells (5 × 10 6 cells/mouse) were subcutaneously injected into nude mice. …
Transcriptional activation of cyclin D1 via HER2/HER3 contributes …
2020年8月1日 · A549 and H1299 contain wild-type EGFR and are resistant to the erlotinib (an EGFR-TKI), while H1650 and HCC827 harbor an EGFR exon 19 deletion, which is the most …
Acquired resistance to cetuximab is mediated by increased PTEN ...
2010年10月28日 · A, HCC827-P and HCC827-CR cells were treated with 100 nM cetuximab, and the cell lysates were hybridized to a phospho-RTK array. B, HCC827-P and HCC827-CR cells …
A homologous and molecular dual-targeted biomimetic …
2023年9月1日 · The HCC827 cells were incubated at 90%–100% confluence in the culture plate wells, and the media were replaced with serum-free media for 24 h. Then, three scratch lines …
Gefitinib resistance of cancer cells correlated with TM4SF5 …
Although HCC827-T790M 2–1 cells were still more gefitinib-resistant compared with the HCC827-T790M 2–1 cells with a suppressed TM4SF5 or p27 Kip1 level, the cells showed a certain …
Discovery of a novel anti PD-L1 X TIGIT bispecific antibody for the ...
2021年1月1日 · HCC827 or Raji-hPD-L1 tumor cells were subcutaneously implanted into the flanks of female NSG mice. When tumors reached volumes of ∼100 mm 3 , 1 × 10 7 freshly …
Molecular profiling of afatinib-resistant non-small cell lung cancer ...
2020年11月1日 · HCC827 and resistant cells were therefore incubated with PHA665752 in combination with either gefitinib or afatinib. As shown in Table 6 , parental HCC827 and …
Antitumor Efficacy of Dual Blockade of EGFR Signaling by …
2018年6月1日 · HCC827, H1975, and PC9T790M NCLC cells were injected subcutaneously into the dorsal flank of nude mice and, after 2 weeks, when tumor size was approximately 200 mm …