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2023年2月23日 · A territory-wide retrospective cohort study was conducted in Hong Kong to investigate the efficacy of MOV and NMV-r against severe outcomes of COVID-19 in unvaccinated adult patients with chronic respiratory diseases.

2024年1月9日 · We conducted a retrospective territory-wide cohort study in Hong Kong to investigate the efficacy of NMV-r and MOL among adult patients who had chronic respiratory diseases (COPD, asthma, bronchiectasis and interstitial lung diseases (ILD)), who were unvaccinated and hospitalized for COVID-19 with moderate severity at …

2025年2月20日 · The therapeutic combination of nirmatrelvir and ritonavir is effective in preventing disease progression and reducing COVID-19 severity. In clinical trials, NMV/r reduced the risk of hospitalization or death by 86%.

If the net market value (NMV) of any single item of securities or investments equals 25% or more of required liquid capital (RLC), shall include in ranking liabilities

2024年4月29日 · This randomized, double-blind, placebo-controlled, multinational trial showed that NMV/r reduced the risk of COVID-19–related hospitalization or death from any cause by 86% when patients were treated within 5 days of symptom onset (0.9% vs. 6.5%, absolute risk in treated vs. placebo, respectively; P < 0.001). 8 In contrast to EPIC-HR, which ...

2023年9月15日 · In December 2021, 2 novel oral antiviral agents—nirmatrelvir/ritonavir (NMV/r) and molnupiravir (MPV)—were granted emergency use authorization by the Food and Drug Administration for treatment of early symptomatic cases of mild to moderate COVID-19 at high risk of progression to severe disease [16–19].

2024年1月9日 · Methods: A territory-wide retrospective study was conducted in Hong Kong to compare the efficacy of NMV-r and MOL against COVID-19 in unvaccinated adult patients with asthma, chronic obstructive pulmonary disease, bronchiectasis and interstitial lung diseases presenting with moderate COVID-19 from 16th February 2022 to 15th March 2023.

Molnupiravir (MOV) and nirmatrelvir/ritonavir (NMV/r) are efficacious oral antiviral agents for patients with the 2019 coronavirus (COVID-19). However, little is known about their effectiveness in older adults and those at high risk of disease ...

Nirmatrelvir/ritonavir (NMV/r) 是一种口服抗病毒药物，适用于对疾病进展为重症高风险的轻度至中度 COVID-19 患者进行门诊治疗。 我们从美国卫生部门的角度评估了 NMV/r 与最佳支持治疗对于具有进展为重症高风险的轻度至中度 COVID-19 患者的成本效益。 使用短期决策树（1 年）和终生 2 状态马尔可夫模型（存活和死亡）开发了成本效益模型。 短期决策树捕获了与原发感染和医疗保健利用相关的成本和结果；假设美国质量调整生命年（QALY），对短期决策树的幸存者进行 …