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2025年2月5日 · Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome of overwhelming inflammation (hyperinflammation) that causes multiorgan failure and death, making...

2023年3月27日 · Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, hyper-inflammatory disorder affecting both newborns and adults alike. The disease is characterized by dysregulated immune activity resulting in malignant inflammation and multi-organ failure.

Hemophagocytic lymphohistiocytosis (HLH) is a rare disease of the immune system. It more often occurs in babies and young children. But it can also occur in adults. In adults, many conditions can cause HLH. This is known as acquired HLH. It can be caused by some infections, cancer, and autoimmune diseases.

2024年6月5日 · HLH causes a hemorrhagic form of DIC with increased risk of bleeding due to low fibrinogen levels. Prior to lumbar puncture, consider checking a fibrinogen level, coagulation studies, and complete blood count. Basic chemistry findings may include elevated protein levels and lymphocytic pleocytosis.

2024年11月7日 · Hemophagocytic lymphohistiocytosis (HLH) is a rapidly progressing, life-threatening syndrome characterized by excessive immune activation, often presenting as a complex cytokine storm. This hyperactive immune response can lead to multi-organ failure and systemic damage, resulting in an extremely short survival period if left untreated.

Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of defective apoptosis, a disruption of the regulatory pathway that terminates immune and inflammatory responses. Fever, cytopenia, splenomegaly, and/or hemophagocytosis are typical findings of ...

Hemophagocytic lymphohistiocytosis (HLH) is an uncommon disorder causing immune dysfunction primarily in infants and young children. Many patients have an underlying immune disorder, although in some patients the underlying disorder is not known. Manifestations may include lymphadenopathy, hepatosplenomegaly, fever, and neurologic abnormalities.

Hemophagocytic lymphohistiocytosis (HLH) is a severe, systemic inflammatory syndrome that can be fatal. This syndrome can sometimes occur in people with medical problems that cause a strong activation of the immune system, such as an infection or cancer. HLH in these settings is called secondary HLH.

Haemophagocytic lymphohistiocytosis (HLH) is a potentially life-threatening syndrome of uncontrolled inflammation, characterised by fever, cytopenias and progressive organ dysfunction. The clinical presentation can vary, often mimicking and sometimes coexisting with sepsis, so the diagnosis is often missed.