2024年7月15日 · Henoch-Schönlein purpura (HSP) is a disease that inflames small blood vessels. The inflammation causes blood vessels in the skin, intestines, kidneys, and joints to start...

2021年9月21日 · Henoch-Schonlein purpura is an inflammation of the small blood vessels of the skin, joints, bowels and kidneys. When blood vessels get inflamed, they can bleed into the skin, causing a reddish-purple rash (purpura). The most striking feature of this form of vasculitis is a purplish rash, typically on the lower legs and buttocks.

Purpura not due to a low platelet count, caused by inflammation in blood vessels of the skin, is the hallmark of HSP. The tetrad of purpura, arthritis, kidney inflammation, and abdominal pain is often observed. However, all four elements of this tetrad are not required for diagnosis.

Henoch–Schönlein purpura (HSP) is a form of leukocytoclastic or small-vessel vasculitis, most often observed in children. It is sometimes called anaphylactoid purpura. HSP results from inflammation of the small blood vessels in the skin and various other tissues within the body.

2020年8月15日 · Henoch-Schönlein purpura, now called immunoglobulin A (IgA) vasculitis, is a systemic, immune complex–mediated, small-vessel leukocytoclastic vasculitis characterized by nonthrombocytopenic...

HSP is the most common vasculitis of childhood. It most commonly affects children 2-8 years of age. Usually affects large joints of lower limbs. Rarely upper limbs. If prescribing oral prednisolone, give 1-2 mg/kg/day (maximum 60 mg/day) or IV methylprednisolone 0.8-1.6 mg/kg/day (maximum 1 g/day) while symptoms persist.

2020年10月21日 · Henoch-Schoenlein purpura (HSP) is an IgA-mediated small-vessel vasculitis caused by deposition of immune complexes within vessel walls >75% of patients with HSP are less than 10 years old, with a peak between ages 4 and 6 years

Henoch-Schönlein purpura (HEH-nok SHOON-line PURR-pyuh-ruh) is a condition that makes small blood vessels get swollen and irritated. This inflammation is called vasculitis (vas-kyuh-LY-tis). It usually affects blood vessels in the skin, joints, intestines, and kidneys.

2025年3月24日 · HSP is not contagious and cannot be passed on to others. What are the symptoms? Symptoms can include: A red/purple skin rash (Purpura). This is usually on the legs, elbows and buttocks. The rash may also be itchy. Painful, often swollen joints, usually around the ankles and knees. Swelling of the hands and feet. Vomiting (being sick).

Henoch Schönlein purpura (HSP) is a disease where small blood vessels called capillaries become inflamed and damaged, producing a rash on the skin called ’purpura’. This information sheet from Great Ormond Street Hospital (GOSH) explains about Henoch Schönlein purpura (HSP), what causes it and how it can be treated.