The heteronuclear single quantum coherence or heteronuclear single quantum correlation experiment, normally abbreviated as HSQC, is used frequently in NMR spectroscopy of organic molecules and is of particular significance in the field of protein NMR.

Hetereonuclear Single Quantum Coherence (HSQC) is used to determine the proton to carbon or heteroatom (often nitrogen) single bond correlations. It is also known as heteronuclear multiple quantum coherence (HMQC).

The HSQC (Heteronuclear Single Quantum Coherence) experiment is used to determine proton-carbon single bond correlations, where the protons lie along the observed F2 (X) axis and the carbons are along the F1 (Y) axis. An edited HSQC spectrum of …

Gained Information: The H eteronuclear S ingle Q uantum C orrelation (HSQC) NMR experiment is a proton-detected 2D experiment that shows you 1H / 13C one-bond connectivity. You will see your 1H spectrum as your direct F2 axis and your 13C spectrum as your indirect F1 axis.

Heteronuclear Single Quantum Coherence (HSQC) is a technique used in NMR spectroscopy to simultaneously record 1H and 13C chemical shifts by coupling 1H nuclei with other NMR-active nuclei directly bonded to them, providing structural information in complex mixtures.

HSQC - Heteronuclear Multiple Quantum Correlation. This 2D experiment correlates the chemical shift of proton with the chemical shift of the directly bonded carbon.

2004年1月12日 · The basic building blocks of the multitude of double and triple resonance experiments available today are the heteronuclear multiple quantum correlation (HMQC) and heteronuclear single quantum correlation (HSQC) experiments.

Modern NMR techniques consist of a seemingly end-less multitude of pulse sequences and remains in a state of continuous evolution. However, two simple building blocks are the root of these experiments, the heteronuclear single quantum coherence (HSQC) and heteronuclear double quantum coherence (HMQC) experiments.

2022年8月28日 · The HSQC (Heteronuclear Single-Quantum Coherence) experiment can assist, as it can suppress the 1 H - 1 H couplings and collapse the multiplets seen in the cross peaks into singlets, which greatly enhances resolution (an example of an HSQC is shown in Figure 4.7.61 b).

2010年7月2日 · 2D HSQC (Heteronuclear Single Quantum Coherence) experiment correlates chemical shifts of directly bound nuclei (i.e. two types of chemical nuclei). For example 1 H, 15 N-HSQC correlates chemical shifts within NH groups. For similar correlations over multiple bonds 2D HMBC experiment can be used.