Two serotypes of the herpes simplex virus, HSV-1 (also known as type 1 or oral) and HSV-2 (type 2 or genital), can establish lifelong latent infections with sensory ganglia. Periodically, the virus reactivates and can cause recurrent cold sores, encephalitis and eye and genital infections.

Herpes Simplex Virus 1 and 2 antibody identifies major viral envelope glycoproteins and core proteins that can be found in the cytoplasm and/or nucleus.

Immunohistochemistry (IHC) using monoclonal and polyclonal antibodies is a useful diagnostic method for detecting pathogen antigens in fixed tissues, complementing the direct diagnosis of infectious diseases by PCR and culture on fresh tissues.

2010年9月1日 · Painful diseases caused by herpes simplex virus (HSV) or varicella zoster virus (VZV, also causes chickenpox)

Immunohistochemistry (IHC) with HSV antibodies is used for identification of the viruses in tissue samples. In this study, two polyclonal antibodies, prepared separately with HSV-1 and HSV-2 immunogens, were characterized in comparison to a monoclonal antibody to HSV-1 (10A3).

HSV are among the most common infectious agents of man and usually are transmitted through close personal contact. The manifestations of infection can be localized (oral lesions HSV I; genital lesions HSV II) or can cause life-threatening systemic infection in …

2017年1月1日 · Methods: Five years of cases at an academic medical center were reviewed for the use of IHC to detect cytomegalovirus (CMV), herpes simplex virus 1 and 2 (HSV-1 and HSV-2), varicella zoster virus (VZV), adenovirus, or polyomavirus (ie, BK or JC). Results: In total, 1,636 viral IHC stains were ordered on 1,099 specimens from 957 cases.

HSV I/II by Immunohistochemistry * Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

We examined 28 paraffin-embedded tissue specimens with histologic evidence of herpes virus infection by in situ hybridization (ISH) utilizing manual capillary action technology (MicroProbe Staining System) and a 21 base synthetic multibiotinylated oligonucleotide probe from the HSV glycoprotein C re …

Immunoperoxidase staining for herpes simplex virus (HSV) I and II produces nuclear and granular cytoplasmic staining of virus infected cells. HSV I and II are part of the herpes virus family that also includes Epstein Barr virus, herpes zoster, and cytomegalovirus.