Hemoglobin A2 (HbA2) is a normal variant of hemoglobin A that consists of two alpha and two delta chains (α 2 δ 2) and is found at low levels in normal human blood. Hemoglobin A2 may be increased in beta thalassemia or in people who are heterozygous for the beta thalassemia gene.

A haemoglobin A2 test is done in order to screen for and/or diagnose a haemoglobin disorder. The HBA2 gene provides instructions for making a protein called alpha-globin.

Investigate for hemolytic anemia, hemoglobinopathies, and thalassemia. Specify on the request form the patient's race or ethnic origin (if known) as well as the date of any transfusions …

Elevated levels of Hemoglobin A2 (HbA2) in a blood test can indicate certain health conditions, most notably beta thalassemia, a blood disorder. Hemoglobin is a protein in your red blood cells that carries oxygen throughout your body.

2019年11月20日 · Hemoglobin electrophoresis is used as a screening test to identify variant and abnormal hemoglobins, including hemoglobin A1 (HbA1), hemoglobin A2 (HbA2), hemoglobin...

本专题将讨论α珠蛋白基因 (HBA1 和 HBA2)检测结果的意义。 这些基因的致病性变异 (常为缺失)可导致α地中海贫血。 α珠蛋白基因检测不能识别β地中海贫血或其他累及β珠蛋白的疾病，如镰状细胞病。 检测指征和受检者的临床医疗详见UpToDate中的其他专题 [1]。 准确性 –确认检测机构是经临床实验室改进法案修正案认证的实验室或其他国家认证实验室 (表 1)。 基因型 –确定检测是否包括α珠蛋白基因测序或一系列变异。 某些实验室仅检测特定的常见变异，这有时不能满足需 …

Quantitative HbA2 determination is the most valuable test for β-thalassaemia carrier identification. Several methods have been set up, but only a few are now recommended for their accuracy.

Hb A2 is eluted from the column resin by a programmed buffer gradient of increasing ionic strength. Hb A2 measurement is best interpreted in conjunction with other testing in the Thalassemia Reflexive Panel and red cell indices and iron supply measurements. HbA2, Hb A2.

Forms part of the haemoglobinopathy screen (see Haemoglobin electrophoresis) for the investigation of thalassaemia and haemoglobinopathies. HbA 2 is usually raised in the beta …

In this study, we established the normal ranges of haemoglobin A2 (HbA2) and haemoglobin F (HbF) levels for normal individuals using this system and also the HbA2 level in beta thalassaemia and haemoglobin E (HbE) individuals.