Just after birth, the level of HbF decreases gradually to <1%, and is replaced mainly by adult hemoglobin (HbA) (∼ 97%). However, higher HbF levels could be associated with HbE/β …

胎儿血红蛋白（HbF）酸洗脱试验 （fetal hemoglobi acid washing test） 正常值. 脐带血呼所有的红细胞均呈阳性，新生儿阳性率为55%~85%，1个月后的婴儿为67% 4~6个月后偶见成人小 …

1999年11月1日 · These data suggest that the high HbF levels in HbE/β thalassemia, and other β thalassemia syndromes, result from increased erythropoietin levels leading to bone marrow …

Low HbF expression in HbE-β + -thalassemia may lead to misdiagnosis of HbE heterozygosity. We aimed to characterize the β - and α-globin genes and the modifying factors related to HbF …

Hemoglobin E (HbE) is a common structural β-hemoglobin variant. Although HbE alone does not cause significant clinical problems, its interactions with other thalassemias produce syndromes …

1999年11月1日 · These data suggest that the high HbF levels in HbE/beta thalassemia, and other beta thalassemia syndromes, result from increased erythropoietin levels leading to bone …

2024年9月30日 · Reactivation of fetal hemoglobin (HbF, α 2 γ 2) potentially alleviates clinical presentation in β-thalassemia. Prolyl hydroxylase domain enzymes (PHDs) play roles in the …

However, higher HbF levels could be associated with HbE/β-thalassemia, a complex thalassemia intermedia with a diverse clinical severity ranging from mild-to-severe anemia. This study …

HbF轻度增高可见于：50%的轻型β-珠蛋白生成障碍性贫血、再生障碍性贫血（AA）、阵发性睡眠性血红蛋白尿（PNH）、真性红细胞增多症、铁粒幼细胞贫血、白血病等。 显著增高见于： …

蓝色线：HbF婴儿血红蛋白氧离曲线；绿色线：HbA成人血红蛋白氧离曲线；红色线：Mb肌红蛋白氧离曲线. 从氧离曲线可以看到，HbF对氧的亲和能力的确高于HbA （随氧分压上升更快达到 …