Our previous studies indicated that hepatitis E virus (HEV) forms membrane-associated particles in the cytoplasm, most likely by budding into intracellular vesicles, and requires the …

2016年8月18日 · This interaction likely promotes the budding of newly assembled HEV virions into multivesicular bodies (MVB). If so, the enveloped viral particle in the MVB would likely be …

2024年12月30日 · In this study, we report that HEV ORF3 can be self-secreted into vesicles and identify Annexin II (ANXA2) as crucial for efficient ORF3 self-secretion and quasi-enveloped …

Our previous studies demonstrated that hepatitis E virus (HEV) requires the multivesicular body (MVB) pathway to release virus particles, suggesting that HEV utilizes the cellular ESCRT …

2013年11月13日 · Our previous studies demonstrated that hepatitis E virus (HEV) requires the multivesicular body (MVB) pathway to release virus particles, suggesting that HEV utilizes the …

To examine whether HEV utilizes the multivesicular body (MVB) pathway to release the virus particles, we analysed the efficiency of virion release from cells upon introduction of small …

The ORF3 protein interacts with the tumor susceptibility gene 101, a critical cellular protein required for the budding of enveloped viruses, through the Pro, Ser, Ala, and Pro (PSAP) motif …

Hepatitis E virus (HEV) infection is typically a self-limiting, acute illness that spreads through the gastrointestinal tract but replicates in the liver. However, chronic infections are possible in …

hev包膜：一种新型非胞溶性病毒释放和免疫逃避机制. hev最初从患者粪便中分离出来，通过免疫电子显微镜目测被分为无包膜粒子。这种病毒粒子的直径为27-34nm并具有20面体的形态。衣 …

2024年10月5日 · This type of HEV was found to utilize the ESCRT and MVB pathways to release eHEV particles, as evidenced by silencing or loss-of-function of TSG101, VPS4A and VPS4B . …