2022年11月9日 · High-flow nasal cannula (HFNC) is a potential alternative treatment in this patient population and may be better tolerated. For patients presenting with acute hypercapnic respiratory failure, is HFNC an effective alternative to NIV in reducing the need for intubation?

HFNC是指一种通过高流量鼻塞持续为患者提供可以调控并相对恒定吸氧浓度（21%~100%）、温度（31~37 ℃）和湿度的高流量（8~80 L/min）吸入气体的治疗方式。该治疗设备主要包括空氧混合装置、湿化治疗仪、高流量鼻塞以及连接呼吸管路 。

High-flow oxygen through nasal cannula (HFNC) provides adequate oxygenation and can be an alternative to noninvasive ventilation (NIV) for patients with hypoxemic respiratory failure. The aim of the present study was to assess the efficacy of HFNC versus NIV in …

To reduce reintubation, a prophylactic high-flow nasal cannula (HFNC) and non-invasive mechanical ventilation (NIV) after extubation are used to improve oxygenation in patients at high-risk of extubation failure. HFNC delivers a heated, humidified, and adjustable air–oxygen mixture through a large-caliber nasal cannula.

2025年1月1日 · We investigated the efficacy and safety of a high-flow nasal cannula (HFNC) at different flow rates compared to noninvasive ventilation (NIV) in patients with acute chronic obstructive pulmonary disease (COPD) exacerbations. This prospective, randomized, single-blind study assigned patients to one of three study groups.

We reviewed the use of noninvasive ventilation (NIV) versus high flow nasal cannula (HFNC) oxygen in adult acute respiratory failure (ARF). We searched major databases and included randomized trials comparing at least NIV with HFNC or NIV+HFNC with NIV in ARF. Primary outcomes included intubation/re …

The findings of our systematic review suggest that sequential NIV may have a better outcome compared to sequential HFNC, while NIV with active humidification was found to be superior to HFNC in preventing reintubation in critically ill patients at a very high risk of extubation failure .

近年来，经鼻高流量湿化氧疗（HFNC）以其对气体加温加湿、提供稳定氧流量、减少死腔通气、提供 气道正压 等特点而广泛应用于临床，包括低氧性呼吸衰竭和 高碳酸血症 性呼吸衰竭。 此外，HFNC作为一种新型氧疗方式，能够提供10～60 L／min高效加温加湿的气体，比普通氧疗更能改善 氧合，比无创机械通气更舒适。 近年来越多临床证据也表明经鼻高流量能够降低插管率、辅助撤机、减少无创通气的实施，但其改善通气、降低二氧化碳、改善呼吸做功、缓解 呼吸肌疲 …

2022年11月9日 · High-flow nasal cannula (HFNC) is a potential alternative treatment in this patient population and may be better tolerated. Research question: For patients presenting with acute hypercapnic respiratory failure, is HFNC an effective alternative to …

2024年7月18日 · A cross-over randomized study showed that both HFNC and NIV treatment for one hour can improve respiratory acidosis and relieve dyspnea in AECOPD patients, and HFNC was more effective than NIV for improving both oxygenation and RR .