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Hemoglobin J is an abnormal hemoglobin, an alpha globin gene variant and present in various geographic locations. It was first reported in a black American family [1] in 1956, and later reported from Indonesia, India, and other parts of the world.

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Here we describe the fortuitous detection of unknown HbJ using capillary electrophoresis for measurement of HbA 1c. A patient followed for gestational diabetes in our laboratory presented unknown haemoglobin on Capillarys 2 Flex Piercing analyser which was identified as HbJ. HbJ is not associated with haematological abnormalities.

We report the case of a very rare haemoglobin variant, “Haemoglobin J”, discovered while performing haemoglobin electrophoresis following low HbA1C value reported in pregnant female with Gestational diabetes mellitus. Haemoglobin J is an alpha chain variant and heterozygous group of fast moving Haemoglobin (FMH).

2022年10月1日 · HbJ is rare variant of hemoglobin with 71 nrw variants till date. CE-HPLC stands as a standard for these hemoglobin variants differentiation where Hb J presents as a P3 peak. Hemoglobin J is defined by a faster movement towards …

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