2025年2月5日 · Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome of overwhelming inflammation (hyperinflammation) that causes multiorgan failure and death, making...

Haemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening, cancer-like disorder in which the immune system becomes overactive, attacking the body's own cells and tissues. Symptoms include fever, enlarged liver and spleen, and low blood cell counts, necessitating urgent medical attention. 1,2 . What is HLH?

In hematology, hemophagocytic lymphohistiocytosis (HLH), also known as haemophagocytic lymphohistiocytosis (British spelling), and hemophagocytic or haemophagocytic syndrome, [1] is an uncommon hematologic disorder seen more often in children than in adults.

Hemophagocytic lymphohistiocytosis in response to EBV or otherwise remains a life-threatening problem for patients with genetic disorders that cause HLH. Discoveries made in recent decades have yielded extraordinary advances in our understanding of HLH. Early recognition and initiation of HLH-directed therapy remain key for patient survival.

HLH is a rare complication of Epstein-Barr virus (EBV) infection. Deficiencies may be characterized by abnormal activity of lymphocyte function leading to hemophagocytosis and multi-organ failure. Although EBV-associated HLH carries a high mortality rate, quick diagnosis and appropriate treatment can subside the disease.

Hemophagocytic lymphohistiocytosis is a rare and often life-threatening condition if left untreated. HLH causes your immune system to attack your body instead of a foreign invader like a virus. The condition is either acquired or genetic and there’s no way to prevent it. Treatment is available and most effective with an early diagnosis.

2023年3月27日 · Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening, hyper-inflammatory disorder affecting both newborns and adults alike. The disease is characterized by dysregulated immune activity resulting in malignant inflammation and multi-organ failure.

Haemophagocytic Lymphohistiocytosis (HLH) is a devastating syndrome with uncontrolled activation of the immune system leading to hyperinflammation, tissue damage and multi-organ failure.

2024年11月7日 · Hemophagocytic lymphohistiocytosis (HLH) is a rapidly progressing, life-threatening syndrome characterized by excessive immune activation, often presenting as a complex cytokine storm. This hyperactive immune response can lead to multi-organ failure and systemic damage, resulting in an extremely sho …

2024年10月30日 · Hemophagocytic lymphohistiocytosis (HLH) is a non-malignant but often fatal disorder of immune dysregulation affecting multiple organs. It is also known as macrophage activation syndrome when occurring in the setting of a rheumatologic disorder. It typically affects infants and young children but can be seen at all ages 5.