The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation of the immune system. [1] The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals.

人類白細胞抗原（英語： Human leukocyte antigen ，缩写： HLA ），是編碼人类的主要组织相容性复合体（MHC）的基因。 其位于 6号染色体 的短臂上（6p21.31），包括一系列紧密连锁的 基因座 ，与人类的 免疫系统 功能密切相关。

人类白细胞抗原 （英语：human leukocyte antigen）- HLA是在6号染色体短臂上的一类基因，编码 MHC蛋白质 。HLA有不同的基因座，编码两大类MHC蛋白。 HLA高度多态性，同一种基因座还有不同的等位基因

2023年4月24日 · Human leukocyte antigens (HLA) are genes in major histocompatibility complexes (MHC) that help code for proteins that differentiate between self and non-self. They play a significant role in disease and immune defense. They are beneficial to the immune system but can also have detrimental effects.

The human MHC is called the HLA (Human Leukocyte Antigen) system because these antigens were first identified and characterized using alloantibodies against leukocytes. 1 Leukocyte-agglutinating antibodies (leukoagglutinins) were observed in sera from multiparous women and previously transfused patients. Graft rejection was found to be ...

The human leukocyte antigen (HLA) system (the major histocompatibility complex [MHC] in humans) is an important part of the immune system and is controlled by genes located on chromosome 6. It encodes cell surface molecules specialized to present antigenic peptides to the T-cell receptor (TCR) on T cells.

人类白细胞抗原（human leukocyte antigen, HLA）是由HLA基因复合体所编码的产物，定位于第6染色体短臂上。HLA系人类组织相容性复合体（MHC）的表达产物，是构成移植排斥反应的重要抗原物质。HLA的研究最初是在器官移植研究推动下开展起来的，故此，HLA又称移植抗原。

在介绍HLA前，我们先了解肿瘤新生抗原（neoantigen），它来源于肿瘤体细胞变异，在肿瘤细胞中特异性表达而产生的抗原物质，可以被T细胞受体特异性识别（图1），引发宿主的免疫反应，在抗肿瘤免疫应答中起着重要作用 [1]。 也就是说，肿瘤新生抗原越多，免疫反应结果越好。 图1. HLA传递肿瘤新生抗原示意图. 人类白细胞抗原是一种存在于人体细胞表面的蛋白，主要用于细胞间识别、抗原识别和抗原呈递，调节免疫应答。 HLA位于人类6号染色体短臂6p21.3上，长度 …

The human leukocyte antigen (HLA) system is one of the most crucial host factors influencing disease progression in bacterial and viral infections. This review provides the basic concepts of the structure and function of HLA molecules in humans.

2013年7月18日 · The Major Histocompatibility complex (MHC) system known as the human leukocyte antigen (HLA) in humans is located on the short arm of chromosome 6 (6p21.3) and contains the most polymorphic gene cluster of the entire human genome.