HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA …

2024年12月25日 · HLA-DOA (Major Histocompatibility Complex, Class II, DO Alpha) is a Protein Coding gene. Diseases associated with HLA-DOA include Hirata Disease. Among its related …

HLA-DO regulates surface presentation of human leukocyte antigen class II-restricted antigens on B cell malignancies. HLA-DOA, HLA-DRA, and HLA-DQA1 associated with spontaneous …

HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In …

hla-ii类基因包括hla-d家族，主要有hla-dp、hla-dq和hla-dr等，主要分布于b淋巴细胞、巨噬细胞和树突状细胞等专职抗原提呈细胞表面。 HLA-III类基因 大约包含75个基因，大多数功能不明。

HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA …

Heterodimer of an alpha chain (DOA) and a beta chain (DOB). Forms a heterotetrameric complex with an HLA-DM molecule during intracellular transport in endosomal/lysosomal compartments …

2024年6月1日 · HLA class II antigen presentation is modulated by the activity of the peptide editor HLA-DM and its antagonist HLA-DO, with their interplay controlling the peptide repertoires …

hla-doa与hla-dob形成异二聚体。 该异二聚体HLA-DO存在于B细胞的溶酶体中，并调节HLA-DM介导的MHC II类分子上的肽加载。 与经典的HLA II类分子相比，该基因在蛋白质水平上的序列变 …

The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II …