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Hemophagocytic lymphohistiocytosis (HLH) is a condition that occurs when your immune system abnormally overreacts. Your immune system defends your body from things that make you sick, like bacteria and viruses. Cells, proteins, organs and tissues work together to keep you healthy.

2024年6月5日 · HLH causes a hemorrhagic form of DIC with increased risk of bleeding due to low fibrinogen levels. Prior to lumbar puncture, consider checking a fibrinogen level, coagulation studies, and complete blood count. Basic chemistry findings may include elevated protein levels and lymphocytic pleocytosis.

Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder of inflammation that was first thought to affect only young infants and children but is increasingly recognized in older children and adults.

Hemophagocytic lymphohistiocytosis, also called HLH, is an immune deficiency disorder. In this type of disorder, part of the immune system is missing or defective. That means the body can’t fight infections as it should. As a result, a person with HLH may have frequent infections that are generally more severe and last longer than usual.

Hemophagocytic lymphohistiocytosis (HLH) is an uncommon disorder causing immune dysfunction primarily in infants and young children. Many patients have an underlying immune disorder, although in some patients the underlying disorder is not known. Manifestations may include lymphadenopathy, hepatosplenomegaly, fever, and neurologic abnormalities.

Hemophagocytic lymphohistiocytosis (HLH) is rare life-threatening syndrome that can affect infants, children, adolescents and adults. HLH is not a single disease, however; it is a group of disorders of the immune system that can be triggered by infections, cancer or …

2024年10月30日 · Hemophagocytic lymphohistiocytosis (HLH) is a non-malignant but often fatal disorder of immune dysregulation affecting multiple organs. It is also known as macrophage activation syndrome when occurring in the setting of a rheumatologic disorder. It typically affects infants and young children but can be seen at all ages 5.

2022年12月15日 · This ICU OnePager reviews Hemophagocytic lymphohistiocytosis (HLH) and Macrophage activation Syndrome (MAS): it's pathogenesis, etiology (primary vs secondary), the diagnostic criteria, and the treatment algorithm.

Hemophagocytic lymphohistiocytosis (HLH) is a severe, systemic inflammatory syndrome that can be fatal. This syndrome can sometimes occur in people with medical problems that cause a strong activation of the immune system, such as an infection or cancer. HLH in these settings is called secondary HLH.