3-Hydroxy-3-methylglutaryl-CoA lyase - Wikipedia
3-Hydroxy-3-methylglutaryl-CoA lyase (or HMG-CoA lyase) is an enzyme (EC 4.1.3.4 that in human is encoded by the HMGCL gene located on chromosome 1. It is a key enzyme in …
HMGCL Gene - GeneCards | HMGCL Protein | HMGCL Antibody
2024年12月25日 · HMGCL (3-Hydroxy-3-Methylglutaryl-CoA Lyase) is a Protein Coding gene. Diseases associated with HMGCL include 3-Hydroxy-3-Methylglutaryl-Coa Lyase Deficiency …
酮体代谢及酮体的多种生理功能 - 知乎 - 知乎专栏
hmg-coa裂解酶（hmgcl）将其裂解，生成乙酰-coa和乙酰乙酸（acac或aa）。 另外，HMGCL还参与亮氨酸的碳架氧化。 D-β-羟丁酸脱氢酶（BDH1）催化乙酰乙酸的还原，生成β羟丁 …
生酮与癌症：酮体会促哪些肿瘤生长？ - 知乎专栏
HMG-CoA裂解酶（HMGCL）是脂肪酸分解为酮体过程（生酮作用）中的关键酶。 BRAF V600E突变在大量黑色素瘤中被发现。 研究 [1] 发现，与BRAF WT对照组相比，BRAF V600E突变细 …
HMGCL 3-hydroxy-3-methylglutaryl-CoA lyase [ (human)]
Gene ID: 3155, updated on 8-Feb-2025. The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine …
3-羟基-3-甲基戊二酰辅酶 A 裂解酶（HMGCL）基因 | MCE
该基因编码的蛋白质属于 HMG-CoA 裂解酶家族。 它是一种线粒体酶，催化亮氨酸降解的最后一步，并在酮体形成中起关键作用。 该基因的突变与 HMG-CoA 裂解酶缺陷有关。 已发现该基因 …
HMGCL 3-hydroxy-3-methylglutaryl-CoA lyase - NIH Genetic …
2025年1月4日 · Clinical resource with information about HMGCL, Deficiency of hydroxymethylglutaryl-CoA lyase, and available tests. There are links to practice guidelines …
Entry - *613898 - 3-HYDROXY-3-METHYLGLUTARYL-CoA LYASE; HMGCL …
2023年2月21日 · 3-Hydroxy-3-methylglutaryl coenzyme A lyase catalyzes the cleavage of HMG-CoA to acetoacetic acid and acetyl-CoA, the last step of both ketogenesis and leucine …
3-羟基-3-甲基戊二酰辅酶A裂解酶缺乏症2例患儿的临床及遗传学 …
3-羟基-3-甲基戊二酰辅酶A裂解酶缺乏症(3-hydroxy-3-methylglutaryl-CoA lyase deficiency，HMGCLD)(OMIM 246450)又称3-羟基-3-甲基戊二酸尿症(3-hydroxy-3 …
HMGCL基因在细胞中的表达调控机制 - 八方基因
本文将详细介绍hmgcl基因在细胞中的表达调控机制，探讨其功能和可能的调控因素，帮助理解该基因在细胞代谢中的重要作用。 HMGCL基因概述 首先，HMGCL 基因，也被称为HL …