2020年11月20日 · TTE or TEE imaging helps guide alcohol septal ablation, particularly in localizing the appropriate left anterior descending septal perforator by intracoronary contrast injection as well as monitoring of LVOT gradient reduction during the procedure.

Hypertrophic cardiomyopathy (HCM, or HOCM when obstructive) is a condition in which muscle tissues of the heart become thickened without an obvious cause. [8] . The parts of the heart most commonly affected are the interventricular septum and the ventricles. [10] .

2020年2月25日 · Hypertrophic cardiomyopathy (HCM) is the most common inherited monogenic cardiac disorder, affecting 0.2-0.5% of the population. 1,2 In the United States, 750,000 people are estimated to have HCM; however, only approximately 100,000 people have been diagnosed, signifying a large gap in the recognition and understanding of this disease. 3 As diag...

2020年11月20日 · For all patients with suspected HCM, a transthoracic echocardiogram (TTE) is recommended. If resting left ventricular outflow tract (LVOT) gradient is <50 mm Hg, provocative testing should be performed. For symptomatic patients without provoked gradients, an exercise echocardiogram should be performed.

2024年6月7日 · Hypertrophic cardiomyopathy (HCM) is an autosomal dominant cardiac myocyte disease caused by mutations in sarcomere and sarcomere-related protein genes encoding for elements of the contractile machinery of the heart.

The 2024 AHA/ACC/AMSSM/HRS/PACES/SCMR Guideline for the Management of Hypertrophic Cardiomyopathy (AHA/ACC/Multisociety HCM Guideline) provides guidance for clinicians on the management of patients with hypertrophic cardiomyopathy (HCM). 1 The guideline contains updated, evidence-based recommendations that build on those from the 2020 HCM Guidel...

Conventional echocardiography (TTE) is the most readily accessible and informative tool in making the diagnosis of HCM. It is also the first noninvasive imaging method for risk stratification, treatment selection and follow-up of patients.

Hypertrophic cardiomyopathy (HCM), a relatively common, globally distributed, and often inherited primary cardiac disease, has now transformed into a contemporary highly treatable condition with effective options that alter natural history along specific personalized adverse pathways at …

2022年2月10日 · Hypertrophic Cardiomyopathy (HCM) is a prominent form of cardiomyopathy characterized by the thickening (hypertrophy) of the heart muscle, particularly the left ventricle. This condition is caused by genetic mutations affecting proteins that play a role in myocardial growth and contraction.

This executive summary of the hypertrophic cardiomyopathy clinical practice guideline provides recommendations and algorithms for clinicians to diagnose and manage hypertrophic cardiomyopathy in adult and pediatric patients as well as supporting documentation to …