2024年12月25日 · HSPA12A (Heat Shock Protein Family A (Hsp70) Member 12A) is a Protein Coding gene. Diseases associated with HSPA12A include Leukoencephalopathy With …

2024年4月8日 · Gain- and loss-of-function studies demonstrated that HSPA12A was required to support cardiomyocyte survival upon hypoxia/reoxygenation (H/R) challenge and that its …

2023年8月14日 · Heat shock protein A12A (HSPA12A) shows decreased expression in the brains of schizophrenia patients. However, the causal effects of HSPA12A in any psychiatric …

2025年2月8日 · Heat-Shock protein A12A is a novel PCNA-binding protein and promotes hepatocellular carcinoma growth. HSPA12A unstabilizes CD147 to inhibit lactate export and …

HSPA12A encodes a novel member of the HSP70 family. Here, we report that NASH patients showed increased hepatic HSPA12A expression and serum HSPA12A contents. Intriguingly, …

HSPA12A acted as a scaffolding protein to binding both p53 and USP10. USP10 mediated the HSPA12A-increased p53 protein stability. Cardiac fibrosis is the main driver for adverse …

2024年11月14日 · Heat-shock protein A12A attenuates oxygen-glucose deprivation/reoxygenation-induced human brain microvascular endothelial cell dysfunction via …

HSPA12A protects the heart against myocardial ischemia/reperfusion injury by maintaining aerobic glycolytic homeostasis and H3 lactylation in cardiomyocytes by increasing Smurf1 …

Targeting HSPA12A in CF could represent a promising strategy for the management of cardiac fibrosis in patients. The present study provided clear evidence that HSPA12A is a novel …

This gene has 30 transcripts (splice variants), 204 orthologues and 4 paralogues. Broad expression in brain (RPKM 23.0), fat (RPKM 11.2) and 16 other tissues. 预测启用 ATP 绑定活 …