2024年12月25日 · HSPA1B (Heat Shock Protein Family A (Hsp70) Member 1B) is a Protein Coding gene. Diseases associated with HSPA1B include Pulmonary Edema and Acute Pancreatitis. Among its related pathways are Autodegradation of the E3 ubiquitin ligase COP1 and Infectious disease.

Human gene HSPA1B is an intron-less gene which encodes for the heat shock protein HSP70-2, a member of the Hsp70 family of proteins. [5] The gene is located in the major histocompatibility complex, on the short arm of chromosome 6, in a cluster with …

Data show that HSPA1B exerts a positive effect on hepatocellular carcinoma (HCC) cell growth and may be involved in the HBV-miR- 340- 5p- ATF7 axis. the presence of HSPA1B 1267GG genotype significantly increases the risk of glaucoma in northern Iran; Downregulation of HSPA1b impaired mesenchymal stem cell osteogenic and chondrogenic ...

这个无内含子的基因编码一个 70kDa 的热休克蛋白，它是热休克蛋白 70 家族的一员。 与其他热休克蛋白结合，该蛋白稳定现有蛋白以防止聚集，并介导新翻译蛋白在胞质溶胶和细胞器中的折叠。 它还通过与富含 AU 的元素 RNA 结合蛋白 1 的相互作用参与泛素-蛋白酶体途径。 该基因位于主要组织相容性复合体 III 类区域，与两个编码相似蛋白质的密切相关基因位于一个簇中。 [RefSeq 提供，2008 年 7 月] This intronless gene encodes a 70kDa heat shock protein which is a …

2024年12月10日 · In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1.

In our study, we found that the expressions of HSPA1B, HSPA4, HSPA5, HSPA6, HSPA8, HSPA9, HSPA13, and HSPA14 were significantly increased, while those of HSPA1A, HSPA2, HSPA7, and HSPA12B were significantly decreased in colon cancer tissues.

2025年1月5日 · In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1.

2024年3月14日 · 70kda热休克蛋白1b（hspa1b）是一种分子量为70千道尔顿的蛋白质，属于热休克蛋白（hsp）家族的一员。 HSPs 是一组在多种环境压力下诱导的蛋白质，如高温、缺氧、化学物质、氧化应激等。

2022年8月15日 · In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1.

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