Somatosensory neuron types identified by high-coverage …
2015年12月22日 · To confirm the existence of C2 subclusters, IB4-negative small neurons (area < 314 μm 2), selected randomly from dissociated DRG neurons, were analyzed by single-cell …
IB4-Binding DRG Neurons Switch from NGF to GDNF
1997年10月1日 · We have tested the role of glial cell line-derived neurotrophic factor (GDNF) in regulating a group of putatively nociceptive dorsal root ganglion (DRG) neurons that do not …
正常和糖尿病小鼠背根神经节中神经元与胶质细胞关联的细胞结构 …
2020年6月24日 · 我们使用整装小鼠腰椎 DRG 制剂、共聚焦显微镜和计算机辅助 3D 分析来揭示 IB4 +非肽能神经元形成 4.7 ± 0.26 个细胞的小簇，不同于 CGRP +大多数情况下，肽能神经元 …
Oxaliplatin Depolarizes the IB4– Dorsal Root Ganglion Neurons to …
We characterized the membrane excitability of IB4 + and IB4 – subpopulations of small DRG neurons, examined the responses of IB4 + and IB4 – DRG neurons to acute oxaliplatin, and …
Patch-seq of mouse DRG neurons reveals candidate genes for …
2021年11月2日 · The distribution of MS currents in DRG neurons has been addressed over the past by distinguishing neuronal subsets using morphological and electrophysiological …
A mouse DRG genetic toolkit reveals morphological and …
2024年3月4日 · The reporter signals detected in DRG neuron cell bodies were compared with signals for three neurochemical makers: CGRP, which labels many small and large diameter …
Impaired Axonal Regeneration by Isolectin B4-Binding Dorsal …
2007年1月31日 · In cultures of dissociated DRG neurons of adult mice on laminin, robust spontaneous neurite outgrowth from IB4-negative neurons occurs and is strongly enhanced by …
IB4-binding DRG neurons switch from NGF to GDNF dependence …
2016年10月7日 · In vitro, GDNF supports the survival of small neurons that express Ret and bind IB4 while failing to support the survival of neurons expressing TrkA and CGRP. Together, our …
Intense isolectin-B4 binding in rat dorsal root ganglion neurons ...
2006年7月5日 · Binding to isolectin-B4 (IB4) and expression of tyrosine kinase A (trkA) (the high-affinity NGF receptor) have been used to define two different subgroups of nociceptive small …
Upregulation of Ih expressed in IB4-negative Aδ nociceptive DRG …
2015年11月18日 · Amongst nociceptive DRG neurons, a mechanically sensitive neuron, isolectin B4 negative Aδ-type (IB4 − Aδ) DRG neuron displays spontaneous activity with …