IGFBP-5 是 IGFBPs 家族中最保守的蛋白，且作为一个主要的调控因子调控细胞的生长和发育等过程。 以 IGF-IGFBP-ALS (acid labie subunit)三聚体形式存在于血液中，这种三聚体的作用是 …

Insulin-like growth factor-binding protein 5 (IBF-5) is a protein that in humans is encoded by the IGFBP5 gene. [5] An IGFBP5 gene was recently identified as being important for adaptation to …

2024年12月25日 · IGFBP5 (Insulin Like Growth Factor Binding Protein 5) is a Protein Coding gene. Diseases associated with IGFBP5 include Insulin-Like Growth Factor I and Pulmonary …

2020年3月3日 · In this review, we survey and discuss what is currently known about IGFBP-5 in normal physiology and human disease. Based on recent in vivo genetic evidence, we suggest …

2020年3月2日 · Among the six distinct types of IGFBPs, IGFBP-5 is the most highly conserved across species and has the broadest range of biological activities. IGFBP-5 is expressed in …

IGFBP-5 expression prevented tumor growth and inhibited tumor vascularity in a xenograft model of human ovarian cancer. These results are the first evidence showing that IGFBP-5 plays a …

胰岛素样生长因子结合蛋白 5 （insulin-like growth factor-binding protein 5， IGFBP5）是一种重要的分泌蛋白，属于IGFBP家族（IGFBP1～IGFBP7），其与多种组织中的炎症和纤维化有关 …

2025年2月8日 · IGFBP5 modulates lipid metabolism and insulin sensitivity through activating AMPK pathway in non-alcoholic fatty liver disease. Downregulation of PAPP-A2 expression or …

igfbp-5 蛋白是 igfbp 家族的成员，可显着延长 igf 的半衰期并调节其在细胞培养中的生长促进作用。 多功能 IGFBP-5 可以通过改变与 IGF 受体相互作用的动力学来抑制或刺激细胞对 IGF 的反 …

Enables insulin-like growth factor I binding activity. Involved in several processes, including cellular response to cAMP; regulation of smooth muscle cell migration; and regulation of …