2015年12月2日 · Background: Pulmonary hypertension (PH) is a common finding in patients with chronic fibrosing idiopathic interstitial pneumonias (IIP). Little is known about the response to pulmonary vasodilator therapy in this patient population.

Pulmonary hypertension, also known as idiopathic pulmonary artery hypertension (IPAH), is a progressive disease that affects the precapillary pulmonary vasculature for which an exact underlying risk factor is unknown. The pulmonary artery pressure is persistently more than 25 mmHg at rest and more than 30 mmHg during exercise.

2015年12月2日 · We retrieved data from COMPERA to compare patient characteristics, treatment patterns, response to therapy and survival in newly diagnosed patients with idiopathic pulmonary arterial hypertension (IPAH) and PH associated with IIP (PH-IIP).

The term idiopathic pulmonary arterial hypertension (IPAH) is used to categorize patients with pre-capillary pulmonary hypertension of unknown origin. There is considerable variability in the clinical presentation of these patients.

Idiopathic pulmonary arterial hypertension (IPAH) is a severe, yet incurable, disease that affects the small pulmonary arteries with vasoconstriction and vascular proliferation, leading to remodelling and an increased pulmonary vascular resistance.

加权基因相关网络分析（wgcna）用于构建ipah的共表达基因网络。 使用 DAVID、基因集富集分析 (GSEA) 和基因集变异分析 (GSVA) 进行基因本体论和通路富集分析。

2024年10月24日 · Idiopathic pulmonary arterial hypertension (IPAH) is a disease of the small pulmonary arteries characterized by vascular proliferation and remodeling. It results in a progressive increase in pulmonary vascular resistance (PVR) and, ultimately, right ventricular failure and death.

2020年7月24日 · 该文提出了“3P”诊断路径以确诊IPAH，以期提高临床上IPAH诊断的准确率。 近年来肺高血压越来越受到重视，其与多个学科数十种疾病相关。 目前根据病因不同将肺高血压分为五大类，许多中心不同学科相继开展了肺高血压的分类诊断与治疗，然而分类诊断的准确率有待进一步提高。 尤其是特发性肺动脉高压（IPAH），作为第一大类肺动脉高压的一个亚型，其诊断需排除所有其他类型肺高血压以及其他亚型肺动脉高压，是肺高血压诊断中的难点和重点。 该 …

2020年4月11日 · IPAH 必须符合肺动脉高压的血流动力学诊断标准，即右心导管测量肺动脉平均压(mean pulmonary artery pressure，mPAP) ≥ 25mmHg，同时肺小动脉楔压(pulmonary artery wedge pressure，PAWP) ≤ 15mmHg 及肺血管阻力(pulmonary vascular resistance，PVR)>3Wood 单位。

2022年10月1日 · Among patients meeting diagnostic criteria for idiopathic pulmonary arterial hypertension (IPAH), there is an emerging lung phenotype characterised by a low diffusion capacity for carbon monoxide (DLCO) and a smoking history. The present study aimed at a detailed characterisation of these patients.