[When to consider type I interferonopathy in adulthood?]
Type I interferonopathies (IP1) are a heterogeneous group of Mendelian diseases characterized by overactivation of the type I interferon (IFN) pathway. They are caused by monogenic (rarely …
IP-3/IP-1 Assays - Assay Guidance Manual - NCBI Bookshelf
2012年5月1日 · The assay is a competitive immunoassay. IP1 produced by cells (in the presence of LiCl) after receptor activation competes with an IP1 analog coupled to a d2 fluorophore …
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I
2005年8月28日 · Using high-throughput functional screening of interferon inducers, we have identified here a molecule we call interferon-β promoter stimulator 1 (IPS-1). Overexpression …
HTRF IP-One细胞水平检测[新品推荐] - 生物通
HTRF IP1测量试剂盒是基于HTRF技术的竞争性免疫检测，使用了铽穴状化合物（Tb cryptate）标记的抗IP1单抗和d2标记的IP1。 G蛋白介导的信号传导通路主要有三种，通过G蛋白的四个亚 …
IP-1: A dominant inhibitor of Fos/Jun whose activity is modulated …
1991年3月8日 · IP-1 specifically blocks DNA binding of AP-1 from nuclear extracts and of in vitro synthesized Fos/Jun proteins. It is a labile protein of 30–40 kd, which exerts its activity only in …
IP-One Gq kit，你值得拥有！ - 知乎 - 知乎专栏
LiCl能够阻止IP1转化为myo-肌醇，当细胞内加入一定浓度的LiCl，可引起IP1的积聚。所以通过测定IP1的含量，可以用于评估Gq通路的活化程度。
HTRF IP-One Gq Detection Kit-Revvity
HTRF IP-One 检测试剂盒可检测肌醇单磷酸的积累，肌醇单磷酸是由磷脂酶 C（PLC）级联激活诱导产生的 IP3 的稳定下游代谢产物。 该试剂盒可直接表征作用于贴壁细胞或悬浮细胞中 Gq …
IP1 Med Chem- Exam 1 Flashcards - Quizlet
IP1 Med Chem- Exam 1. Flashcards. Learn. Test. Match. Flashcards. Learn. Test. Match. Created by. zimmera9. Terms in this set (12) phenylethylamine is the parent compound for …
IP-1射频灌注泵 - APT Med
IP-1射频灌注泵是一款用于心脏射频消融术的辅助治疗设备，在手术中搭配冷盐水导管，提供稳定，可变的盐水灌注，实时监测气泡及泵管情况。 兼容多种型号泵管、兼容多种射频仪，并支 …
Covalent inhibitors of interleukin-2 inducible T cell kinase (itk) with ...
2012年11月26日 · The analogues are highly potent in a cellular IP1 assay as well as in a human whole-blood (hWB) assay. Despite a half-life of approximately 2 h in resting primary T cells, …