Interleukin-1 receptor-associated kinase 1 (IRAK-1) is an enzyme in humans encoded by the IRAK1 gene. [5] [6] IRAK-1 plays an important role in the regulation of the expression of …

2024年12月25日 · IRAK1 (Interleukin 1 Receptor Associated Kinase 1) is a Protein Coding gene. Diseases associated with IRAK1 include Pediatric Systemic Lupus Erythematosus and …

Interleukin-1 receptor activated kinases (IRAKs) are key mediators in the signaling pathways of TLRs/IL-1Rs. By means of their kinase and adaptor functions, IRAKs initiate a cascade of …

IRAK1 is a threonine/serine kinase. Unlike IRAK4, IRAK1 is not a core constituent of the Myddosome but transiently interacts with IRAK4 upon Myddosome assembly. Unlike IRAK4, …

2024年5月9日 · Interleukin receptor-associated kinase (IRAK) proteins are pivotal in interleukin-1 and Toll-like receptor-mediated signaling pathways. They play essential roles in innate …

2014年10月7日 · Interleukin-1 receptor-associated kinase (IRAK) family members are mediators of TLR/IL1R superfamily signalling, and mounting evidence implicates these kinases as viable …

IRAK1 Is a Critical Mediator of Inflammation-Induced Preterm Birth. A new insight into thymosin beta4, a promising therapeutic approach for neurodegenerative disorders. Polymorphisms of …

2008年2月1日 · Interleukin-1 receptor activated kinases (IRAKs) are key mediators in the signaling pathways of TLRs/IL-1Rs. By means of their kinase and adaptor functions, IRAKs …

该基因编码白细胞介素 1 受体相关激酶 1，这是两种推定的丝氨酸/苏氨酸激酶之一，在刺激后与白细胞介素 1 受体 (IL1R) 相关。 该基因部分负责 IL1 诱导的转录因子 NF-kappa B 的上调。 已 …

IRAK1 is a class of serine-threonine protein kinases related to IL-1R and TLR signaling that plays a major role in initiating the innate immune response against foreign pathogens. From: …