2011年4月14日 · Interferon regulatory factor 7 (IRF7) was originally identified in the context of Epstein–Barr virus (EBV) infection, and has since emerged as the crucial regulator...

2024年12月25日 · IRF7 (Interferon Regulatory Factor 7) is a Protein Coding gene. Diseases associated with IRF7 include Immunodeficiency 39 and Primary Immunodeficiency With …

2023年8月9日 · The inhibitory domain (ID) located between 341 and 467 aa interferes with the transactivation function of IRF7, but primarily within the region of 416–467 aa, and this …

IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus …

Interferon regulatory factor 7 (IRF7), a member of the interferon regulatory factors (IRFs) family, is located downstream of the pattern recognition receptors (PRRs)-mediated signaling pathway …

2000年11月3日 · The present structure-function studies have identified multiple regulatory domains in the C-terminal region of IRF-7 that contribute to transactivation. A constitutive …

Interferon regulatory factor 7 (IRF7) was originally identified in the context of Epstein–Barr virus (EBV) infection, and has since emerged as the crucial regulator...

2024年5月20日 · All IRFs bind DNA via a conserved amino-terminal winged helix–loop–helix domain with five regularly spaced tryptophan residues (Fig. 1a). This domain recognizes …

The signal response domain (SRD) or accessory inducibility region located at the C-terminal end between 468 and 503 aa mediates IRF7 dimerization and contains a serine-rich domain, and …

Interferon regulatory factor 7 (IRF7) was originally identified in the context of Epstein–Barr virus (EBV) infection, and has since emerged as the crucial regulator of type I interferons (IFNs) …