Monoclonal Antibody for studying IRP1. Cited in 11 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, IRP1 (D6S4J) Rabbit Monoclonal Antibody (CST #20272) is ready to ship.

IRP-1 Antibody (E-12) is a mouse monoclonal IgG2a kappa light chain antibody that detects IRP-1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA).

Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation. #P40924

Click on the product pages below for more detailed antibody information including target specificity, validated applications and product-specific citations. Your search returned 10 IRP1 Antibodies across 4 suppliers. Select up to 5 products from below to …

AA range:681-730 Phospho-IRP-1 (S711) Polyclonal Antibody detects endogenous levels of IRP-1 protein only when phosphorylated at S711. The protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells.

ACO1, or IRP1, is a bifunctional protein that functions as an iron-responsive element (IRE)-binding protein involved in the control of iron metabolism by binding mRNA to repress translation or degradation. It functions also as the cytoplasmic isoform of aconitase.

IRP-1 (R134) pAb detects endogenous levels of IRP-1 protein. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). Synthetic peptide, corresponding to amino acids 100-150 of Human IRP-1. For research use only, not for use in diagnostic procedure.

相关研究表明铁调节蛋白1 (irp1/aco1)通过调控低氧诱导因子2α以及铁下垂等过程在多种疾病的发生发展进程中发挥重要作用。本文着重介绍了irp1在肿瘤、神经退行性疾病、血液系统疾病中的作用，最后总结irp1在医学中的潜在应用价值及未来前景。

2006年7月18日 · Iron regulatory proteins 1 and 2 (IRP1 and IRP2) are mammalian proteins that register cytosolic iron concentrations and post-transcriptionally regulate expression of...

IRP1 (D6S4J) Rabbit mAb recognizes endogenous levels of total IRP1 protein. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu734 of human IRP1 protein.