DNA 结合抑制因子 2（ID2）基因 | MCE - MCE-生物活性分子 ...
DNA 结合抑制剂家族的成员通过 HLH 结构域抑制它们的异二聚化伙伴，以显性负性方式抑制基本螺旋-环-螺旋转录因子的功能。 这种蛋白质可能在负向调节细胞分化中发挥作用。 该基因的 …
ID2 Gene - GeneCards | ID2 Protein | ID2 Antibody
2024年12月25日 · ID2 (Inhibitor Of DNA Binding 2) is a Protein Coding gene. Diseases associated with ID2 include Ewing Sarcoma and Retinoblastoma. Among its related pathways …
肿瘤医生应该知道的生物标志物之：IDH1/IDH2 - 知乎
IDH1/2是人类癌症中最常发生突变的代谢基因，干扰细胞代谢和表观调节，促进癌症发生。 【解释】： IDH1和IDH2编码异柠檬酸脱氢酶1和2，催化异柠檬酸氧化脱羧成ɑ-酮戊二酸（α-KG） …
IDH突变、表观遗传与靶向治疗 - 知乎 - 知乎专栏
IDH是三羧酸循环的限速酶，能够催化异柠檬酸使之氧化脱羧生成α-KG和CO2。 由IDH催化的这一反应不仅是TCA循环上不可缺少的一个环节，还是细胞内NADPH/NADH等物质的重要来源之 …
ID2人源基因|ID2基因突变_致病性_靶点-RDDC官网
DNA结合抑制剂家族成员以显性负方式抑制基本螺旋-环-螺旋转录因子的功能，通过HLH结构域抑制其异二聚化伴侣。 这个蛋白质可能参与负调控细胞分化。 这个基因的一个假基因位于染色 …
IDH2 - Wikipedia
Isocitrate dehydrogenase is a digestive enzyme that is used in the citric acid cycle. Its main function is to catalyze the oxidative decarboxylation of isocitrate into alpha-ketoglutarate.
IDH2 Gene - GeneCards | IDHP Protein | IDHP Antibody
2024年12月25日 · IDH2 (Isocitrate Dehydrogenase (NADP (+)) 2) is a Protein Coding gene. Diseases associated with IDH2 include D-2-Hydroxyglutaric Aciduria 2 and Multiple …
ID2 inhibitor of DNA binding 2 - NIH Genetic Testing Registry …
2024年6月17日 · Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their …
ID2 癌基因 - 癌症123
Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization …
IDH2 gene: MedlinePlus Genetics
At least two mutations in the gene have been found to cause a type of 2-hydroxyglutaric aciduria known as D-2-hydroxyglutaric aciduria (D-2-HGA) type II. This condition has a variety of signs …
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