1996年10月25日 · The detailed structure of the IgG presented here, and the distribution of effector binding sites, appears consistent with effector activation mechanisms involving …

Geis illustrates the structure of an antibody, immunoglobulin G (IgG), which was first revealed by X-ray crystallography in 1977 (Silverton et al., 1978). His depiction was published in …

SAbDab is a database containing all the antibody structures available in the PDB, annotated and presented in a consistent fashion. Each structure is annotated with a number of properties …

免疫球蛋白G (Immunoglobulin G，IgG)是在 脾脏 和 淋巴结 中合成，在血清中的含量最高 (占Ig量的75%)，而且在血清中半衰期长，主要分布在血清和组织液中，是抗细菌、抗毒素和抗病毒 …

IgG is the most common class of antibodies used in therapy and possesses two identical heavy chains (HC) and light chains (LC), each of which is composed of a constant and variable region...

We present the crystal structure at 2.7 angstrom resolution of the human antibody IgG1 b12. Antibody b12 recognizes the CD4-binding site of human immunodeficiency virus-1 (HIV-1) …

Complete structural coordinates were generated by combining the Brookhaven X-ray coordinate files for the human IgG1 Fc (1fc2.pdb) and F (ab') (2ig2.pdb) fragments after symmetrically …

Download scientific diagram | Structural features of intact IgG (A), camelid hclgG (B), and shark IgNAR (C) antibody formats shown as surface representation (top) as well as ribbon and …

2019年6月20日 · Here, we use our reported individual-particle electron tomography (IPET) method with optimized negative-staining (OpNS) for direct 3D reconstruction of individual IgG …

The crystallizable fragment (Fc) of the immunoglobulin class G (IgG) is an attractive scaffold for the design of novel therapeutics. Upon engineering the C-terminal loops in the CH3 domains, …