白介素-17（IL-17）已经发现的成员有6个，分别是：IL-17A、IL-17B、IL-17C、IL-17D、IL-17E（也被称为IL-25）和IL-17F。 随着研究的深入，IL-17产生细胞除了TH17细胞外，还有很 …

IL-17F utilizes IL-17RA and IL-17RC as its receptors and activates the MAP kinase-related pathway. IL-17F is derived from several cell types such as Th17 cells, mast cells and …

IL-17C. IL-17C was identified during the search for IL-17A-related cytokines (Li et al. 2000). IL-17C is mainly expressed by epithelial cells following stimulation with TLR2 and TLR5 ligands …

2020年2月26日 · This body of evidence has paved the way for the first clinical trials attempting to neutralize IL-17C in patients. Here, we review the latest knowledge about identification, …

2023年10月11日 · IL-17 is a highly versatile proinflammatory cytokine necessary for vital processes including host immune defenses, tissue repair, inflammatory disease pathogenesis, …

IL-17C is a unique cytokine that is produced by keratinocytes and that is involved in such synergistic loops that may be responsible for amplifying the inflammation in both diseases. …

2018年7月1日 · IL-17C is a keratinocyte-produced cytokine that is overexpressed in atopic dermatitis and psoriasis. An IL-17C antibody improves skin inflammation in models and in …

2020年2月25日 · In this review, we provide an overview of expression patterns and the functional importance of IL-17C and its receptor IL-17RE in immunological diseases, present a …

2018年10月24日 · IL-17C, which is a member of the IL-17 family of cytokines, is preferentially produced by epithelial cells in the lung, skin and colon, suggesting that IL-17C may be …

2024年12月25日 · IL17C (Interleukin 17C) is a Protein Coding gene. Diseases associated with IL17C include Anal Gland Neoplasm and Cutaneous Candidiasis. Among its related pathways …