
Dose-Dependent Effects of IL-17 on IL-13–Induced Airway …
2013年4月15日 · These IL-13–induced responses were variably affected by coadministration of IL-17: lower doses of IL-17 enhanced eosinophil recruitment to the airways, at the same time …
Interleukin-17 and its target genes: mechanisms of interleukin-17 ...
Interleukin-17 (IL-17) has emerged as a central player in the mammalian immune system. Although this cytokine exerts a host-defensive role in many infectious diseases, it promotes …
白细胞介素17研究最新进展,Science和Nature双双见刊~ - 知乎
il-17在保护性免疫和免疫病理中的作用. il-17细胞因子家族成员具有多种生物学功能,促进对多种病原体的保护性免疫,但也在感染和自身免疫过程中驱动炎症病理。il-17驱动的炎症通常是由 调 …
A phase I, randomized, observer-blinded, single and multiple
2019年1月7日 · Background: Inhibition of interleukin (IL)-13, a Type 2 inflammatory mediator in asthma, improves lung function and reduces exacerbations; however, more effective therapies …
IL-17: 一个人的“骑兵队” - 知乎 - 知乎专栏
白介素17(il-17)作用于各种细胞靶标,导致细胞活化。il-17对内皮细胞的作用导致炎症和促凝血活性。当作用于上皮细胞和成纤维细胞时,il-17会导致细胞因子和酶的产生。在单核细胞和树 …
IL-13-producing Th1 and Th17 cells characterize adaptive
In helper T cells, IL-13 is traditionally considered a Th2-type cytokine that is coexpressed with IL-4. Using mouse models of immunization and autoimmunity, we demonstrate that IL-13 is …
我和 IL4 是好兄弟——IL13 - 丁香通
2017年9月1日 · 白细胞介素-13(Interleukin-13)是白介素家族的重要成员,是由 IL-13 基因编码生成的蛋白质,分子量约 10KD。IL-13 可由多种细胞分泌,如 CD4+T 细胞、CD8+T 细胞、 …
白介素IL-13生物学功能及其受体信号通路 - 知乎
IL-13是内皮细胞 VCAM-1 的强效诱导剂,增加人肺成纤维细胞上ß1整合素和VCAM-1的表达,并增加肌肉对乙酰胆碱的收缩反应。 在上皮细胞中,IL-13是Eotaxin的强效诱导剂,还能诱 …
Basic biology and role of interleukin-17 in immunity and inflammation
Interleukin-17 (IL-17, also known as IL-17A) is a key cytokine that links T cell activation to neutrophil mobilization and activation. As such, IL-17 can mediate protective innate immunity …
IL-13受体:炎症和癌症治疗的热门靶点 - Sino Biological
IL-13是内皮细胞VCAM-1的强效诱导剂,增加人肺成纤维细胞上ß1整合素和VCAM-1的表达,并增加肌肉对乙酰胆碱的收缩反应。在上皮细胞中,IL-13是Eotaxin的强效诱导剂,还能诱 …