Interleukin 21 - Wikipedia
Interleukin 21 (IL-21) is a protein that in humans is encoded by the IL21 gene. [5] [6] [7] Interleukin-21 is a cytokine that has potent regulatory effects on cells of the immune system, …
肿瘤治疗多效细胞因子——IL21 - 知乎 - 知乎专栏
其中， 白介素IL21 （Interleukin 21）是主要的免疫调节剂之一，通过影响多种免疫细胞来调节各种免疫应答。百奥动物开发了 B-hIL21R mice ，为临床前药效评估提供了优质模型。 关于靶 …
我是两面派，↓ B 细胞，↑T 细胞——IL21 － 丁香通
2017年9月1日 · IL-21 是作用于 B 细胞的一类免疫抑制因子, 可以抑制 B 细胞淋巴瘤细胞亚群的增殖, IL-21 也可能在调节 B 细胞肿瘤发生方面具有作用。 IL-21 在鼠的原始 B 细胞可诱导 Stat1 …
IL-21：多效到惊呼厉害的细胞因子 - 知乎 - 知乎专栏
IL-21是一种四螺旋束的细胞因子，对淋巴细胞和骨髓细胞具有多种生物学效应。 IL-21主要由活化的CD4+ T细胞、NK细胞、TFH细胞、Th17细胞分泌，增强免疫细胞的抗原特异性反应，促 …
Interleukin-21: a double-edged sword with therapeutic potential
2014年4月22日 · Interleukin-21 (IL-21) is a pleiotropic cytokine that is composed of four α-helical bundles and produced primarily by natural killer T (NKT) cells, T follicular helper (T FH) cells …
IL-21: a novel IL-2–family lymphokine that modulates B, T, and …
2003年7月23日 · IL-21 is a recently described type I cytokine produced by activated CD4 + T cells that profoundly affects the growth, survival, and functional activation of B, T, and natural killer …
什么是白细胞介素21(IL-21)？ - 知乎
白细胞介素21 (IL-21)对免疫细胞具有强烈的调节作用，包括可破坏病毒感染的 自然杀伤细胞 (NK)和 细胞毒性T细胞。 该细胞因子可诱导靶细胞分裂/增殖。 IL-21表达于人活化的CD4+T …
IL-21 Signaling in Immunity - PMC - PubMed Central (PMC)
IL-21 is a type I cytokine produced by T cells and natural killer T cells that has pleiotropic actions on a wide range of immune and non-immune cell types. Since its discovery in 2000, extensive …
IL21 Gene - GeneCards | IL21 Protein | IL21 Antibody
2024年12月25日 · IL21 (Interleukin 21) is a Protein Coding gene. Diseases associated with IL21 include Immunodeficiency, Common Variable, 11 and Il21-Related Infantile Inflammatory …
IL-21: a pleiotropic cytokine with potential applications in oncology
Interleukin- (IL-) 21 is a pleiotropic cytokine that regulates the activity of both innate and specific immunity. Indeed, it costimulates T and natural killer (NK) cell proliferation and function and …