2024年12月25日 · INHBB (Inhibin Subunit Beta B) is a Protein Coding gene. Diseases associated with INHBB include Eclampsia and Pre-Eclampsia. Among its related pathways are Signaling by TGFB family members and Peptide hormone metabolism. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and growth factor activity.

Inhibin, beta B, also known as INHBB, is a protein which in humans is encoded by the INHBB gene. [5] [6] INHBB is a subunit of both activin and inhibin, two closely related glycoproteins with opposing biological effects.

2024年8月26日 · In this paper, we review the different expression patterns, functions, and mechanisms of INHBB in normal and tumor tissues to illustrate the research prospects of INHBB in tumor progression. • INHBB is a gene that encodes the inhibin βB subunit, which forms part of the TGF-β superfamily of proteins that regulate various cellular processes.

该基因编码 TGF-β (转化生长因子-β) 蛋白质超家族的成员。 编码的前原蛋白经过蛋白水解处理，生成二聚体激活素和抑制素蛋白复合物的一个亚基。 这些复合物分别激活和抑制垂体分泌促卵泡激素。 该基因附近的多态性与女性人类患者的先兆子痫有关。 [RefSeq 提供，2016 年 8 月] This gene encodes a member of the TGF-beta (transforming growth …

2020年10月6日 · Background: Inhibin subunit beta B (INHBB) is a protein-coding gene that participated in the synthesis of the transforming growth factor-β (TGF-β) family members. The study is aimed at exploring the clinical significance of INHBB in patients with colorectal cancer (CRC) by bioinformatics analysis.

INHBB is an established locus for ER-negative breast cancer, and HABP2 and LINC01483 represent putative new breast cancer susceptibility loci; Results found that INHBB expression was reduced in nasopharyngeal carcinoma (NPC) tissues, and …

2023年10月22日 · gc 细胞和成纤维细胞之间可促进 gc 进展的 inhbb/nf-kb/il-1b 正向调节反馈回路的示意图。 总之，我们的研究表明，inhbb在gc细胞和成纤维细胞之间创造了一个促进肿瘤的局部炎症环境，从而为inhbb在gc发生和发展中的作用提供了新的证据（图8k）。

抑制素是性腺分泌的一种糖蛋白激素，它具有抑制垂体促卵泡素合成和分泌的作用。 本文介绍了抑制素α亚基基因（INHA）、抑制素βA亚基基因（INHBA）、抑制素βB亚基基因（INHBB）的克隆、结构、定位、多态性、表达、分子调节及其与繁殖性能和癌症的关系。 绵羊INHA、INHBA和INHBB基因分别被定位到2q41→q43、4q26和2q31→q33。 INHA、INHBA和INHBB基因对绵羊产羔数都有显著的影响。 抑制素βB亚基基因突变的雌性小鼠有明显的发育和繁殖缺陷。 INHA …

2023年5月1日 · Inhibin subunit beta B (INHBB) was upregulated in GBM and predicted poor survival. It promoted tumor growth, invasion and stemness in GBM. INHBB expression correlated with the epidermal growth factor receptor (EGFR) expression and downstream AKT and ERK expression levels.

Animal-Free INHBB Protein, Human (His) 是在大肠杆菌中表达产生的一种无动物成分的重组蛋白，在 C 末端带有 His 标签。 INHBB 蛋白复杂地控制垂体功能，调节卵泡刺激素和激活素。 它的关键作用延伸到多种生理过程，包括激素分泌、细胞发育、胰岛素释放和骨骼生长。 INHBB Protein, Human (HEK293, His) 是重组的 INHBB 蛋白，由 HEK293 表达，带有 C-10*His 标签。 INHBB Protein, Human (HEK293, His) 全长 379 个氨基酸，分子量分别约为 ~17.52 & 40.53 & 53.75 …