The interleukin 4 (IL4, IL-4) is a cytokine that induces differentiation of naive helper T cells (T h 0 cells) to T h 2 cells. Upon activation by IL-4, T h 2 cells subsequently produce additional IL-4 in a positive feedback loop.

白 细胞 介素-4（ 白介素-4, Interleukin-4, IL-4 ）是II型 辅助T细胞 （ Th2细胞 ）分泌的 细胞因子 。 白细胞介素-4的生物作用，包括刺激活化B细胞和 T细胞 增殖、 CD4+T细胞 分化成II型 辅助T细胞 .

il-4 增强pha刺激t细胞释放 gm-csf 和 g-csf 。 白介素4（il-4）可诱导幼稚辅助性t细胞（th0细胞）分化为 th2细胞 。通过il-4激活后，th2细胞随后在正反馈回路中产生其他il-4。il-4主要由肥大细胞，th2细胞，嗜酸性粒细胞和嗜碱性粒细胞产生。 白细胞介素4的受体称为 il ...

Interleukin-4 (IL-4) is a four-α-helical bundle type I cytokine with broad pleiotropic actions on multiple lineages. Major actions of IL-4 were initially discovered for B and T cells, but this cytokine acts on more than a dozen different target cells spanning the innate and adaptive immune systems and is produced by multiple different cellular ...

Interleukin-4 is a cytokine that is produced by various cells and plays a role in exerting anti-inflammatory effects during infections like tuberculosis. AI generated definition based on: Tuberculosis, 2009

2025年1月1日 · Interleukin-4 (IL-4), which is traditionally associated with inflammation, has emerged as a key player in tissue regeneration. Produced primarily by T-helper 2 (Th2) and other immune cells, IL-4 activates endogenous lymphocytes and promotes M2 macrophage polarization, both of which are crucial for tissue repair.

2005年7月19日 · Interleukin-4 (IL-4) is a cytokine produced by T(H)2 type helper T cells and by mast cells, basophils, and eosinophils. This cytokine can elicit many responses, some of which are associated with allergy and asthma. Studies with long-term cell lines and primary cells have revealed differences in the …

白细胞介素-4（白介素-4, Interleukin-4, IL-4）是II型辅助T细胞（Th2细胞）分泌的细胞因子。 白细胞介素-4的生物作用，包括刺激活化 B细胞 和 T细胞 增殖、 CD4+T细胞分化成II型辅助T细胞.

Interleukin 4 (IL-4) is a pleiotropic type I cytokine that controls both growth and differentiation among haemopoietic and non-haemopoietic cells. Its receptor is a heterodimer. One chain, the IL-4R alpha chain, binds IL-4 with high affinity and determines the …

2022年8月22日 · Interleukin-4 (IL-4) CD4+T cells (Th2) synthesize IL-4, and it acts on both B and T cells. It is a B-cell growth factor and causes IgE and IgG1 isotype selection. It causes Th2 differentiation and proliferation, and it inhibits IFN gamma-mediated activation on macrophages. It promotes mast cell proliferation in vivo. Interleukin-5 (IL-5)