The Filaggrin gene (FLG) is one of the 70 genes forming the Epidermal Differentiation Complex (EDC), a 2MB region located on human chromosome 1q21. These genes are responsible for the maturation of keratinocytes, which are the chief cells in human epidermis.

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Read all the papers in 2024 IEEE International Symposium on Information Theory (ISIT) | IEEE Conference | IEEE Xplore

丝聚蛋白（filaggrin, FLG）是人体皮肤角质层中连接角蛋白纤维的重要分子，在FLG单体协助连接下，角蛋白纤维规则地聚集，在表皮的最外层形成坚实的物理屏障，可以防止表皮水分的丢失和外界过敏物质的入侵。

To address this, we developed a robust and cost-effective high-throughput PCR-based method for analyzing the entire coding region of FLG using Fluidigm microfluidics technology and next-generation sequencing (NGS). We have applied this method to fully resequence cohorts of Chinese, Malay, and Indian patients with AD from the Singaporean population.

The major determinant of FLG expression in the skin are loss-of-function mutations in FLG, the strongest genetic risk factor for atopic dermatitis (AD), an inflammatory skin disease characterized by a reduced skin barrier function.

Ichthyosis vulgaris is caused by loss-of-function mutations in the filaggrin gene (FLG) and is characterized clinically by xerosis, scaling, keratosis pilaris, palmar and plantar hyperlinearity, and a strong association with atopic disorders.

Signals and NRv1 Route update has been released with 8 Quick Drive scenarios. FLG product prices will be increased by 10% from 1st January 2025. Hello all, There is important news for all members.

2021年3月15日 · 这部时长12分钟45秒的纪录短片名为《外国团体的崛起：法 轮 功》（The Rise of Foreign Groups: Falun Gong），由美国女演员兼导演安德里亚·威尔逊（Andrea Wilson）担任制片人、作家兼导演亚当·戴维斯（Adam Davis）执导，透过镜头详细披露了“法 轮 功”的起源、发展和现状，曝光了法 轮 功 在其发展过程背后的真相，记录了 法 轮 功如何从一个邪教组织演变成极端政治组织，成为一把悬在美国人民头上的无形之剑。 视频中文内容如下： 法 轮 功鼓动信 …

ISIT offers solutions for the development and deployment of real-time embedded systems, specializing in the fields of safety and cybersecurity. As part of the STMicroelectronics Ecosystem, ISIT addresses economic sectors where embedded electronics play a major role: aeronautics/space, automotive/transport, medical, industry, telecommunications ...