2024年12月25日 · ISYNA1 (Inositol-3-Phosphate Synthase 1) is a Protein Coding gene. Diseases associated with ISYNA1 include Congenital Myopathy 4A, Autosomal Dominant. Among its …

We demonstrate that SLC5A3 is essential to support a myo-inositol auxotrophy in AML. The commonality among SLC5A3-dependent AML lines is the transcriptional silencing of ISYNA1, …

该基因编码肌醇-3-磷酸合成酶。 编码的蛋白质通过催化葡萄糖 6-磷酸向肌醇 1-磷酸的限速转化，在肌醇生物合成途径中发挥关键作用。 已观察到该基因编码多种亚型的选择性剪接转录变 …

2025年2月9日 · The myo-inositol biosynthesis rate-limiting enzyme ISYNA1 suppresses the stemness of ovarian cancer via Notch1 pathway. Musashi2 promotes the progression of …

Assigned HPA protein class (es) for the encoded protein (s). Number of protein-coding transcripts from the gene as defined by Ensembl. A summary of the overall protein expression profile …

Title: The myo-inositol biosynthesis rate-limiting enzyme ISYNA1 suppresses the stemness of ovarian cancer via Notch1 pathway. Musashi2 promotes the progression of pancreatic cancer …

2023年7月1日 · Here, we report ISYNA1, the rate-limiting enzyme in myo-inositol biosynthesis, as a suppressor of OC regulating cancer stemness. We identified ISYNA1 as a differentially …

isyna1 缺陷促进 oc 细胞在体外和体内的生长、迁移和侵袭能力。isyna1 的敲低增加了 oc 细胞的干性，包括自我更新、csc 标志物表达、aldh 活性、+ /cd117 + csc。相反，异位过表达 …

Here, we report ISYNA1, the rate-limiting enzyme in myo-inositol biosynthesis, as a suppressor of OC regulating cancer stemness. We identified ISYNA1 as a differentially expressed gene in …

2024年5月5日 · Clinical resource with information about ISYNA1, An atlas of genetic influences on human blood metabolites., Large-scale genotyping identifies 41 new loci associated with …