2024年12月25日 · ITGBL1 (Integrin Subunit Beta Like 1) is a Protein Coding gene. Diseases associated with ITGBL1 include Spinocerebellar Ataxia 27A and Myasthenic Syndrome, …

2020年3月5日 · In our present studies, we have found that integrin beta-like 1 (ITGBL1) was enriched in the plasma EVs of CRC patients with lung and liver metastasis. ITGBL1 was first …

Integrin subunit beta like 1 is a protein that in humans is encoded by the ITGBL1 gene. [5] This gene encodes a beta integrin-related protein that is a member of the EGF-like protein family. …

2022年1月23日 · In this study, ITGBL1 preferentially inhibited integrin activity at the trailing edges to promote cell migration. ITGBL1-depleted cells showed increased focal adhesions at the …

2025年2月8日 · Title: Integrin β-like 1 protein (ITGBL1) promotes cell migration by preferentially inhibiting integrin-ECM binding at the trailing edge. Screening differentially expressed genes …

2021年1月6日 · 课题组采用第二代测序等方法分析了大肠癌患者组织、血液标本，发现了整合素β亚基样蛋白1（ITGBL1）在大肠癌肝、肺转移的中的作用。...

2023年8月19日 · ITGBL1 is an important functional mediator between fibroblast-cardiomyocyte crosstalk and could be an effective target for cardiac remodelling in HF patients.

本研究通过RT-qPCR检测人HCC组织中ITGBL1的表达情况，探讨其蛋白表达水平与患者临床病理学参数及预后的关系，以及ITGBL1基因在HCC细胞株中的作用，为寻找新的肝癌预后标志物 …

ITGBL1 promotes gastric cancer cell proliferation and invasion via Akt signal pathway. ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural …

This gene encodes a beta integrin-related protein that is a member of the EGF-like protein family. The encoded protein contains integrin-like cysteine-rich repeats. Alternative splicing results in …

ITGBL1 inhibited integrin-ECM interactions and promoted chondrogenic differentiation in cells. ITGBL1 depletion reduced ECM deposition and led to cartilage damage, whereas …

ITGBL1 overexpression promoted migration and invasion in SMMC-7721 and HepG2 cells in vitro and in vivo, whereas knockdown or knockout ITGBL1 in CSQT-2 cells significantly reduced …

2024年9月5日 · ITGBL1 is a gene that is mainly expressed in fibroblasts, plays an important role in cardiac fibroblast migration, and whose expression is significantly increased in the failing …

Integrin subunit beta-like 1 (ITGBL1), a member of the epidermal growth factor (EGF)-like protein family, encodes a beta integrin-related protein that is mainly associated with the development …

ITGBL1 inhibited immune cell cytotoxicity against melanoma cells by inhibiting NK cells cytotoxicity and counteracting beneficial effects of anti-PD1 treatment, both in vitro and in vivo. …

2022年1月23日 · Integrin β-like 1 protein (ITGBL1) promotes cell migration by preferentially inhibiting integrin-ECM binding at the trailing edge

ITGBL1-depleted cells showed increased focal adhesions at the membranous traces of trailing edges to prevent the retraction of trailing edges. In contrast, overexpression of ITGBL1 …

2020年3月10日 · Integrin, beta-like 1 (ITGBL1) is a β-integrin-related extracellular matrix (ECM) protein. Recently, studies on ITGBL1 have been increasing, and it was reported that ITGBL1 …

2023年11月21日 · Integrin subunit beta-like 1 (ITGBL1), a member of the epidermal growth factor (EGF)-like protein family, encodes a beta integrin-related protein that is mainly associated with …

2015年8月13日 · Here, we present clinical and experimental evidence to clarify the role of the integrin β-like 1 (ITGBL1) as a key contributor to bone metastasis of breast cancer.