
JAG2 - Wikipedia
Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate …
JAG2 Gene - GeneCards | JAG2 Protein | JAG2 Antibody
2024年12月25日 · JAG2 (Jagged Canonical Notch Ligand 2) is a Protein Coding gene. Diseases associated with JAG2 include Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 27 and …
Notch信号通路介绍(及调控基因介绍) - 知乎专栏
Notch受体是一种跨膜受体,包括Notch1-4四种亚型,在信号通路的激活中起到核心作用。 JAG1-2和DLL1:编码Notch的配体,与Notch受体相互作用来启动信号通路。 JAG1和JAG2属 …
Notch 信号转导 - Cell Signaling Technology (CST)
经处理的受体随后通过内体转运到质膜,从而通过 Deltex 调控和 NUMB 抑制的方式与配体结合。在哺乳动物信号发送细胞中,Delta-like(DLL1、DLL3、DLL4)和 Jagged(JAG1、JAG2) …
JAG2 jagged canonical Notch ligand 2 [ (human)] - National …
JAG2-mediated Notch activation confers phenotypic and functional aspects of Langerhans cell histiocytosis to dendritic cells. JAG2 is often expressed by CD138(+) primary cells. Our results …
锯齿状典型 Notch 配体 2(JAG2)基因 | MCE - MCE-生物活性 ...
Notch 信号通路是一种细胞间信号机制,对胚胎的正常发育至关重要。 Notch 基因家族的成员编码对各种细胞命运决定至关重要的跨膜受体。 由该基因编码的蛋白质是激活 Notch 和相关受体 …
JAG2 jagged canonical Notch ligand 2 - NIH Genetic Testing …
2025年1月4日 · Clinical resource with information about JAG2, Muscular dystrophy, limb-girdle, autosomal recessive 27, and available tests. There are links to practice guidelines and …
Jagged2 targeting in lung cancer activates anti-tumor immunity …
2024年4月19日 · Jag2-/-lung tumors exhibited higher frequencies of macrophages that expressed immunostimulatory mediators and triggered T cell-dependent anti-tumor immunity. …
A form of muscular dystrophy associated with pathogenic variants in JAG2
2021年5月6日 · JAG2 encodes the Notch ligand Jagged2. The conserved Notch signaling pathway contributes to the development and homeostasis of multiple tissues, including …
Entry - *602570 - JAGGED 2; JAG2 - OMIM
2021年10月13日 · The JAG2 gene encodes a transmembrane protein that is a ligand for the Notch (see NOTCH1, 190198) family of transmembrane receptors that are critical for various …