2001年11月15日 · Here we show that in addition to inhibiting caspases, the IKK/NF-κB pathway negatively modulates TNF-α-mediated JNK activation, partly through NF-κB-induced X …

2001年11月15日 · Here we report that NF-κB complexes downregulate the c-Jun amino-terminal kinase (JNK) cascade 3, thus establishing a link between the NF-κB and the JNK pathways. …

2004年10月15日 · During an inflammatory response, NF-κB activation antagonizes apoptosis induced by tumor necrosis factor (TNF)-α, a protective activity that involves suppression of the …

Emerging evidence show that JNK promoted tumour progression is involved in various cancers, that include human pancreatic-, lung-, and breast cancer. The pro-survival JNK oncoprotein …

JNK，（c-Jun 氨基末端 激酶，c-Jun N-terminal kinase）又被称为应激活化 蛋白激酶 (stress-activated protein kinase, SAPK)，是 哺乳类 细胞中 MAPK （mitogen -activated protein …

the NF-kB and JNK pathways. Tang et al.35 and De Smaele et al.36 have independently demonstrated that TNFa induces prolonged JNK activation in NF-kB activation-deficient cells,

With respect to TNFalpha, the NF-kappaB-mediated suppression of apoptosis involves inhibition of the c-Jun-N-terminal kinase (JNK) cascade.

2010年11月28日 · Several signal transduction pathways such as NF- κ B and JNK are involved in the pathogenesis of these viruses. For example, the HCV core and HBx proteins are the most …

c-Jun N末端激酶（JNKs）是丝裂原激活的蛋白激酶（MAPK）信号通路的成员，在许多疾病的发病机理中都起着关键作用，包括癌症，炎症，帕金森氏病，阿尔茨海默氏病，心血管疾病，肥 …

2021年5月25日，来自长江大学—赫拉德茨˙克拉洛韦大学 (捷克)毒理学联合实验室的 吴庆华 和 Kamil Kuca 教授团队在 Alzheimer's & Dementia 在线发表了题为 《Hypothesis: JNK Signaling …