JMJD1C Gene - GeneCards | JHD2C Protein | JHD2C Antibody
2024年12月25日 · JMJD1C (Jumonji Domain Containing 1C) is a Protein Coding gene. Diseases associated with JMJD1C include Angelman Syndrome and Central Nervous System …
JMJD1C - Wikipedia
Jumonji domain containing 1C is a protein that in humans is encoded by the JMJD1C gene. [5] The protein encoded by this gene interacts with thyroid hormone receptors and contains a …
Targeting JMJD1C to selectively disrupt tumor T - Nature
2024年2月14日 · Overall, this study identifies JMJD1C as an epigenetic hub that can integrate signals to establish tumor T reg cell fitness, and we present a specific JMJD1C inhibitor that …
JMJD family proteins in cancer and inflammation
2022年9月1日 · The JMJD1 subfamily includes JMJD1A, JMJD1B, and JMJD1C (or KDM3A, B, and C, respectively), which all contain 2 conserved domains required for catalytic activities, 25, …
最新！我国学者揭示JMJD1C在浆细胞分化和类风湿关节炎中的作用
2022年8月23日 · Jmjd1c 是包含 JmjC 结构域的组蛋白去甲基化酶的成员，通过去除靶基因位点上的H3K9me2以促进基因转录，与白血病肿瘤发生、雄性配子发生和脂肪生成有关。
王晓明团队合作揭示肿瘤Treg细胞特异性的表观遗传调控机制及靶 …
2024年2月15日 · 该研究揭示了JMJD1C作为肿瘤Treg适应性的关键表观遗传分子，通过协同抑制AKT和STAT3信号以实现TME中Treg细胞的适应性，并提供了一种特异性的靶点以选择性破 …
Jmjd1c demethylates STAT3 to restrain plasma cell ... - Nature
2022年8月22日 · Here, we found that the expression of Jmjd1c, a member of JmjC domain histone demethylase, in B cells but not in other immune cells, protected mice from rheumatoid …
JMJD1C jumonji domain containing 1C [ (human)] - National …
2025年2月9日 · JMJD1C is the autosomal gene where variants have been demonstrated to be associated with Testosterone (one of Cardiovascular disease risk factors) at genome-wide …
Protein & Cell | 陈默揭示染色质因子JMJD1C通过相分离调控多种 …
2024年11月6日 · 2024年10月25日，清华大学医学院 陈默 课题组于 Protein & Cell 杂志在线发表题为 JMJD1C forms condensates to facilitate a RUNX1-dependent gene expression program …
Targeting JMJD1C to selectively disrupt tumor Treg cell fitness ...
JMJD1C deletion enhanced AKT signals in a manner dependent on histone H3 lysine 9 dimethylation (H3K9me2) demethylase and STAT3 signals independently of H3K9me2 …