JNK Activation Turns on LPS- and Gram-Negative Bacteria
2017年6月13日 · JNK inhibitors SP600125 and TCSJNK6o, and a TLR4 inhibitor TAK242 suppress reactive oxygen species production and NETosis in LPS-, but not PMA-treated …
LPS-Induced Low-Grade Inflammation Increases Hypothalamic JNK ...
Metabolic endotoxemia contributes to low-grade inflammation in obesity, which causes insulin resistance due to the activation of intracellular proinflammatory pathways, such as the c-Jun N …
黄芪多糖通过抑制NF-κB和JNK信号通路减轻LPS诱导的小鼠心肌细胞凋亡
本研究采用LPS诱导小鼠心肌细胞凋亡，通过检测相关凋亡因子表达水平及其在心肌组织中的浸润情况，阐明APS通过抑制NF-κB和JNK信号通路减轻LPS诱导的小鼠心肌细胞凋亡。
Ulinastatin attenuates LPS-induced inflammation in mouse
2018年1月11日 · These results suggested that UTI suppressed LPS-induced NF-κB activation partially by inhibiting LPS-induced Thr183 p-JNK signaling pathways and thus exerted a potent …
Selective inhibition of JNK located on mitochondria protects …
LPS induces JNK activation and JNK mitochondrial localization in mice. To further observe the role of the mitochondria-JNK interaction in LPS-induced ALI/ARDS, the activation of JNK …
The role of macrophage–fibroblast interaction in lipopolysaccharide ...
2021年11月13日 · LPS promotes JNK signaling pathway activation and endogenous TNF-α secretion in pulmonary macrophages, which could facilitate lung fibroblasts aerobic glycolysis …
CHPG通过调控mGluR5表达及JNK信号通路抑制LPS诱导的小胶质细胞激活
方法 在正常的和基因敲减mGluR5的小胶质细胞中,用脂多糖 (LPS)建立炎症模型,通过Griess实验、酶联免疫吸附试验、免疫印迹法、流式细胞术等方法,探测CHPG对LPS诱导的炎症反 …
脂多糖 (LPS) 在 MC3T3-E1 细胞中通过 JNK 途径诱导 ... - X-MOL
在我们之前的研究中，我们发现 LPS 通过激活丝裂原活化蛋白激酶 (MAPKs) 途径，如 c-Jun N 端激酶 (JNK) 和细胞外信号调节激酶 (ERK1/2) 来促进破骨细胞分化和活性。
DUSP8通过JNK/p38 MAPK通路来改善LPS诱导的巨噬细胞炎症反 …
利用100 ng/mL LPS刺激野生型C57BL/6小鼠骨髓来源巨噬细胞 (bone marrow derived macrophage,BMDM),分别在不同时间点收取细胞,实时PCR和Western印迹检测发现LPS处理 …
JNK Activation Turns on LPS- and Gram-Negative Bacteria …
2017年6月13日 · Here we show that Escherichia coli LPS (0111:B4; 10–25 μg/ml), but not phorbol myristate acetate (PMA), activates JNK in human neutrophils in a dose-dependent …