2021年6月23日 · Metformin For Longevity. Metformin is a prescription drug indicated for diabetes but was found to promote longevity in people with type 2 diabetes; Metformin works by inhibiting mitochondria which forces the body to respond by making more mitochondria for use when the drug is not around

6 天之前 · If you like what we do, please feel free to support the channel through the link below.☕ buymeacoffee.com/jrecollegeHost: Joe Rogan ...

2021年6月18日 · Open questions: Is metformin a type of exercise mimetic? How much of metformin's benefit could be achieved by lifestyle interventions such as exercise? Both overlap in activating the Nrf2 and AMPK cellular pathways.

2019年7月1日 · Here’s my opinion on the NYT story on metformin inhibiting benefits of exercise (EX). It’s known that EX-mimetics counter EX. Resveratrol does. Metformin is a mild mito poison that reduces beneficial ROS. My solution: take metformin at night or EX days off. 1.2M subscribers in the JoeRogan community.

2022年11月27日 · PBM gag clauses are illegal as of Oct 2018. See here: https://patientengagementhit.com/news/gag-clause-bills-signed-into-law-improves-healthcare-transparency. They used to exist. Lots of pharmacists did the right thing and ignored them even when they were in effect, but they’re history now.

2019年9月11日 · Why does metformin decrease physical performance? David has a hypothesis – Metformin is interfering with our mitochondria and disrupts its energy production Because of this, later on, the body responds by making more mitochondria to make up for the energy loss (hence the benefit of metformin) David’s Workout Routine

2023年7月11日 · Dr. Sinclair’s NMN supplement research is the topic on Joe Rogan’s podcast, and why he and his family to take NMN + resveratrol + metformin. Update: The Joe Rogan video is no longer available, but I summarize the interview below.

2019年1月30日 · How does metformin work? There are 3 pathways related to aging: AMP-activated protein kinase (AMPK) – metformin targets this pathway; Sirtuin pathways – NMN and resveratrol help with this one; mTOR – this is a pathway in the …

2021年8月25日 · Here are five takeaways I got from the interview (#4 is the most exciting). 1. Metformin, a drug used to treat Type 2 diabetes, may help reverse aging. 2. David uses an Oura ring and an Eight...

The Longevity Experts (@longevity2.0). 25 Likes. Reverse Aging with NMN & Metformin by Dr David Sinclair at Joe Rogan podcast.