Clonal HLA-A*0201-expressing K562 (K562/A*0201) cells were able to process and present endogenously expressed and exogenously loaded melanoma peptide antigens to HLA-A*0201 …

K562 cells were the first human immortalised myelogenous leukemia cell line to be established. K562 cells are of the erythroleukemia type, and the cell line is derived from a 53-year-old …

We set out to generate a library of K562 cells transduced with common MHC class I and II antigens and costimulatory molecules for use as aAPC. We identified an inherent …

2014年1月1日 · Fixed gene-modified K562 can serve as effective aAPC to expand CMV-specific cytotoxic T lymphocytes for therapeutic use in patients after stem cell transplantation. Our …

为了寻找用于ELISPOT测定的替代APC，用HLA-A * 0201基因转染了本身在细胞表面上不表达I类和II类HLA分子的人慢性骨髓性白血病细胞系K562。 表达HLA-A * 0201的克隆K562（K562 / …

Clonal HLA-A*0201-expressing K562 (K562/A*0201) cells were able to process and present endogenously expressed and exogenously loaded melanoma peptide antigens to HLA-A*0201 …

人类细胞周期蛋白cyclin A2是细胞周期蛋白家族中重要的一员,参与Gl/S期和G2/M期调控,在DNA复制,转录和肿瘤转化和发展过程中有非常重要的作用.cyclin A2在许多肿瘤中过表达,可以当作肿 …

结论：（1）两细胞株染色休均为超二倍体结构，具有复杂染色体核型异常； （2）K562/A02细胞株为Bcr-abl融合基因高表达细胞株； （3）两细胞株之Bcr-abl融合基因abl激酶区DNA序列均 …

Here we identified novel human leucocyte antigen (HLA)-A*0201 (HLAA2)-restricted cytotoxic T lymphocyte (CTL) epitopes from a B cell specific molecule HLA-DOβ (DOB) as a potential …

Results: We further generated K562-based MHC class I-negative aAPC line by zinc-finger nuclease mediated insertion of costimulatory molecules into the AAVS1 locus. This aAPC line …