KLF14 - Wikipedia
Krüppel-like factor 14, also known as basic transcription element-binding protein 5 (BTEB5) is a protein that in humans is encoded by the KLF14 gene. [5] The corresponding Klf14 mouse gene is known as Sp6.
KLF14 Gene - GeneCards | KLF14 Protein | KLF14 Antibody
2024年12月25日 · KLF14 (KLF Transcription Factor 14) is a Protein Coding gene. Diseases associated with KLF14 include Diabetes Mellitus and Maturity-Onset Diabetes Of The Young. An important paralog of this gene is KLF16. ... Belongs to …
转录因子KLF14通过抑制HK2调节脓毒症巨噬细胞糖酵解
2022年2月12日 · 上海交通大学医学院附属第一人民医院麻醉科李金宝教授团队于2022年1月在著名免疫学杂志《Cellular & Molecular Immunology》发表题目为《The transcription factor KLF14 regulates macrophage glycolysis and immune function by inhibiting HK2 in sepsis》的文章。 本文第一作者为袁圆、范广健、刘玉齐，通讯作者为姚良芳、陈峰和李金宝教授。 【背景介绍】 脓毒症是全球范围内的主要死亡原因，被定义为因宿主对感染的反应失调而引起的危及生命的多器 …
KLF14 KLF transcription factor 14 [ (human)] - National Center for ...
2025年2月8日 · KLF14 plays an important role in increasing glucose uptake and insulin sensitivity by the activation of PI3-kinase/Akt signaling pathway in vitro. KLF14 transcription is significantly downregulated, whereas Plk4 transcription is upregulated in multiple types of cancers, and there exists an inverse correlation between KLF14 and Plk4 protein ...
KLF14 KLF transcription factor 14 [ Homo sapiens (human) ]
Title: KLF14/miR-1283/TFAP2C axis inhibits HER2-positive breast cancer progression via declining tumor cell proliferation. KLF14 regulates the growth of hepatocellular carcinoma cells via its modulation of iron homeostasis through the repression of iron …
The transcription factor KLF14 regulates macrophage glycolysis …
2022年1月4日 · Here, we provide evidence to support the function of KLF14, a novel Krüppel-like transcription factor, in the regulation of glycolysis and the immune function of macrophages during sepsis....
The role of KLF14 in multiple disease processes - PubMed
Kruppel-like factor 14 (KLF14) is a newly identified member of the KLF family. Expression of KLF14 is induced by TGF-β in intrauterine and ectodermal tissue. Initial researches on KLF14 focused on its role in lipid and glucose metabolism.
KLF14基因 - 百度百科
他们发现，一种名为klf14的基因与皮下脂肪内多种基因水平有关，这表明，klf14是控制这些基因的“总开关”。 这些受KLF14控制的基因与新陈代谢特点，即身高体重指数、肥胖、胆固醇、胰岛素和葡萄糖水平有关。
转录因子KLF家族的结构、功能及调控机制研究进展 - 知猫论文
2024年11月30日 · Klf14基因在血脂异常小鼠肝脏模型中的表达水平降低，表明Klf14基因的表达可能与胆固醇逆向转运有关。
KLF 转录因子 14（KLF14）基因 | MCE - MCE-生物活性分子大师
编码的蛋白质作为转录共抑制因子发挥作用，并通过转化生长因子-β (TGF-β) 诱导抑制 TGF-β 受体 II 基因表达。 该基因在胚胎和胚胎外组织中表现出来自母体等位基因的印迹表达。 [RefSeq 提供，2013 年 7 月] This intronless gene encodes a member of the Kruppel-like family of transcription factors.