
KIR3DL2:杀伤细胞免疫球蛋白样受体(KIR)家族蛋白,T细胞淋 …
2024年2月28日 · 杀伤细胞免疫球蛋白样受体(Killer Cell Immunoglobulin-like Receptors, KIR,即CD158)是一个由14个多态性基因编码的受体家族(KIR2DL1、2DL2、2DL3、2DL4 …
浅谈NK细胞受体 KIR的功能与临床意义 - 搜狐
2021年2月2日 · 杀伤细胞免疫球蛋白样受体( kir s)在记忆性t细胞和nk细胞上表达,是 nk细胞功能的关键调节因子 。kir及其配体mhc-i类(hla-a、-b、-c)分子具有高度多态性,特殊的相互 …
IPD-KIR Database - EMBL-EBI
The IPD-KIR Database provides a centralised repository for human KIR sequences. Killer-cell Immunoglobulin-like Receptors (KIR) have been shown to be highly polymorphic at the allelic …
The peptide selectivity model: Interpreting NK cell KIR-HLA-I …
2024年12月1日 · We hypothesize that a critical discriminating factor in KIR–HLA-I interactions is the selective detection of HLA-I-bound peptides by KIRs. We propose a ‘peptide selectivity …
Understanding how combinations of HLA and KIR genes influence …
Combinations of HLA and killer cell immunoglobulin–like receptor (KIR) genes have been associated with diseases as diverse as autoimmunity, viral infections, reproductive failure, and …
NK细胞的HLA和KIR的配型-上篇 - 知乎 - 知乎专栏
本文从基础hla和kir生物学知识开始,回顾分析国外多年积累的临床数据,以期对这一话题进行一个详细的总结。 目录. 一、hla的生物学原理. 二、kir的生物学原理. 三、利用hla与kir的匹配性优 …
Killer cell immunoglobulin-like receptors (KIR) and human …
2020年3月17日 · HLA-C is a ligand of killer cell immunoglobulin receptors (KIRs) and is an essential regulator of natural killer cell activity, which is associated with endometriosis...
Immunogenomics of Killer Cell Immunoglobulin-Like Receptor (KIR…
2022年7月1日 · Interactions of killer cell immunoglobin-like receptors (KIR) with human leukocyte antigens (HLA) class I regulate effector functions of key cytotoxic cells of innate and adaptive …
kir‐mapper: A Toolkit for Killer‐Cell Immunoglobulin‐Like Receptor (KIR …
2 天之前 · Here, we present kir-mapper, a toolkit to analyse KIR genes from short-read sequencing, focusing on detecting KIR alleles, copy number variation, as well as SNPs and …
Immunogenomics of killer cell Ig-like receptor (KIR) and HLA class …
Interactions of killer cell immunoglobin-like receptors (KIR) with human leukocyte antigens (HLA) class I regulate effector functions of key cytotoxic cells of innate and adaptive immunity. The …