2024年12月25日 · KLK2 (Kallikrein Related Peptidase 2) is a Protein Coding gene. Diseases associated with KLK2 include Prostate Disease and Prostate Cancer. Among its related …

Kallikrein-2 is a protein that in humans is encoded by the KLK2 gene, and is particularly associated with prostatic tissue. [3] [4] [5] [6]

KLK又称 血管舒缓素，是 激肽系统 的主要限速酶，它是一组存在于多数组织和体液中的 丝氨酸 蛋白酶，是一种 肽链 内切酶。 它特异性的在碳末端切割底物肽，可裂解 激肽原 释放具有活性 …

Recombinant hK2 activates ERK1/2 signaling of prostate cancer cell lines, which express both PAR1 and PAR2. The two novel ETV4 fusion partners possess as predominant common …

The KLK2 gene (initially termed human glandular kallikrein 1, hGK-1 and later human kallikrein 2, hK2) was first cloned from a human genomic library by using a mouse tissue kallikrein cDNA …

2014年12月5日 · Human kallikrein-related peptidase 2 (KLK2) is a tryptic serine protease predominantly expressed in prostatic tissue and secreted into prostatic fluid, a major …

2023年6月21日 · klk在癌症中具有促肿瘤（klk3、klk7）或抑肿瘤（klk10）作用。 KLK中过多的分子网络机制，包括与 uPA 、 PAR 、 激肽 、 TGF-b 和 MMP 之间的串扰，共同促进癌细胞的 …

2022年1月31日 · Kallikrein-related peptidases (KLKs) are critical regulators of the tumour microenvironment. KLKs are proteolytic enzymes regulating multiple functions of bioactive...

Recent data suggested that tissue human kallikrein 2 (KLK2) might be involved in the carcinogenesis and tumor metastasis of prostate cancer (PCa). However, the detailed …

Background: Kallikrein-related peptidase 2 (KLK2)-like KLK3 (prostate-specific antigen [PSA])-belongs to the highly conserved serine proteases of the glandular kallikrein protein family (KLK …