
KMUP | Muppet Wiki | Fandom
KMUP is the TV network run by the Muppets on Muppets Tonight. The network was owned by Omnivore Industries until it was bought by Ernst Stavros Grouper in episode 205. KMUP has a number of different areas, including a sound stage, control room, dressing rooms, lobby, commissary, basement, and roof.
KMUP-1 - 维基百科,自由的百科全书
KMUP-1 是一種 黄嘌呤 衍生物,具有 磷酸二酯酶抑制劑 活性 [1]。 ^ KMUP-1 suppresses RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss: roles of MAPKs, Akt, NF-κB and calcium/calcineurin/NFATc1 pathways. PLoS ONE. 2013, 8 (7): e69468. PMC 3723916 . PMID 23936022. doi:10.1371/journal.pone.0069468.
Xanthine Derivative KMUP-3 Alleviates Periodontal Bone
2025年2月26日 · Conclusions: Our study demonstrated that KMUP-3 attenuates Pg-LPS-enhanced osteoclastogenesis and macrophage pyroptosis. Notably, KMUP-3 alleviates alveolar bone loss in experimental periodontitis rats and thus suggests its certain role in safeguarding against periodontal bone resorption.
KMUP-1改善神經性疼痛經由抑制脊髓背角ERK及NF-κB之路徑
神經性疼痛是一個會影響周邊或中樞自體感覺系統的疾病,發生於神經系統有原發性損害或功能不良時,對感覺傳遞的傷害;當周邊神經損害時,會誘導痛覺過敏、觸覺疼痛與自發性疼痛。而神經性疼痛的病人,比起其他慢性疼痛的病人而言,有著更高的疼痛指數。 慢性疼痛被歸為發炎性疼痛 ...
KMUP-1通过介导NO / cGMP / PKG信号通路调节慢性肾功能衰竭 …
目的通过介导NO / cGMP / PKG途径探讨KMUP-1在慢性肾功能衰竭(CRF)血管钙化中的潜在机制,为CRF治疗提供新的见解。 方法采用有/无L-NNA(一种NOS抑制剂)的KMUP-1处理CRF大鼠,然后通过ELISA,茜素红染色,Von Kossa染色,Masson三色染色,Sirius红染色和CD3免疫组化染色进行处理。 同时,从大鼠收集血管平滑肌细胞(VSMC),以证实KMUP-1通过NO / cGMP / PKG途径体外对血管钙化的作用。 此外,分别通过蛋白质印迹和qRT-PCR确定蛋白质 …
Optimizing myocardial cell protection with xanthine derivative KMUP …
To assess whether a xanthine derivative (KMUP-3) treatment coincides with enhanced autophagy while also providing cardio-protection, we investigated the hypothesis that KMUP-3 treatment activation of autophagy through PI3K/Akt/eNOS signalling offered cardioprotective properties.
高醫藥學系系學會 KMUP - Facebook
請運動員們提早10分鐘到場檢錄喔~在場上盡情揮灑汗水吧! 高醫藥學系系學會 KMUP. 1,848 likes · 10 talking about this. 高雄醫學大學藥學系學生會.
KMUP-1 ≥98% (HPLC) | Sigma-Aldrich - MilliporeSigma
Contact Technical Service for assistance. storage temp. KMUP-1 is a soluble guanylyl cyclase activator and PDE inhibitor. Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’. Already Own This Product?
KMUP-1 | inhibitor/agonist | CAS 81996-46-5 - InvivoChem
KMUP-1 是一种黄嘌呤衍生物,已被证明可以调节平滑肌中的 K+ 通道活性,并且是 NO/sGC/cGMP 途径的刺激剂。 KMUP-1 可防止 STZ 对 MA 反应性、eNOS 水平和 KATP 通道的损害,从而防止糖尿病大鼠的血管功能障碍。 KMUP-1 显着减弱 STZ 刺激的 MA 对高 K+ 的反应,这表明 KMUP-1 可能部分恢复 MA 的血管反应性。 此外,STZ 降低内皮一氧化氮合酶 (eNOS) 的表达,并且这种作用被 KMUP-1 逆转,表明 KMUP-1 可以改善 STZ 诱导的血管内皮功能障 …
KMUP-4 | 主动脉舒张剂 | MCE - MCE-生物活性分子大师
KMUP-4, as a xanthine derivative with cGMP-enhancing activity, induces aortic relaxation through endothelium-dependent and independent mechanisms. KMUP-4 increases cytoplasmic cyclic guanosine monophosphate (cGMP) and cyclic adenosine monophosphate (cAMP) levels by inhibiting phosphodiesterases ( PDEs) and activating K+ channels.